| Literature DB >> 1203048 |
E Gerke, W Juchelka, U Mittmann, J Schmier.
Abstract
Systolic intramyocardial pressure (IMP) is measured with a modification of the "closed perfusion technic" in 3 different layers of the myocardium in 8 anesthetized mongrel dogs. In the subendocardium IMP exceed left ventricular pressure (LVP) by about 30% whereas it is 30% lower than LVP in the subepicardium. Under resting conditions the level of isobaric balance of IMP and LVP is at a distance of 57% from the epicardium. During thoracic aortic constriction the ratio of IMP/LVP increases in the subepicardium but decreases in the subendocardium. Occlusion of the left circumflex coronary artery for 30 seconds results in a decrease of IMP and IMP/LVP in the ischemic region. In 25% of all cases, however, an increase of these parameters is found.Entities:
Mesh:
Year: 1975 PMID: 1203048 DOI: 10.1007/bf01906385
Source DB: PubMed Journal: Basic Res Cardiol ISSN: 0300-8428 Impact factor: 17.165