Literature DB >> 12028034

Early lymphocyte recovery post-autologous haematopoietic stem cell transplantation is associated with better survival in Hodgkin's disease.

Luis F Porrata1, David J Inwards, Ivana N Micallef, Stephen M Ansell, Susan M Geyer, Svetomir N Markovic.   

Abstract

A retrospective study of 82 patients was conducted to determine the relationship of absolute lymphocyte count (ALC) recovery with clinical outcome after autologous stem cell transplantation (ASCT) in Hodgkin's disease (HD). The median overall (OS) and progression-free survival (PFS) times from the day of transplantation were significantly better for the 41 patients with ALC > or = 0.5 x 10(9) cells/l compared with the 41 patients with ALC < 0.5 x 10(9) cells/l ("not yet reached" versus 42 months, P < 0.0001; 57 versus 15 months, P < 0.002 respectively). Thus, ALC recovery on day 15 post ASCT in HD is associated with better survival and requires further study.

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Mesh：

Year:  2002        PMID： 12028034     DOI： 10.1046/j.1365-2141.2002.03478.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


  24 in total

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Journal:  Nat Biotechnol       Date:  2008-03-30       Impact factor: 54.908

2.  Infusion of autograft natural killer cell/CD14+HLA-DRDIM cell ratio predicts survival in lymphoma post autologous stem cell transplantation.

Authors:  A Kansagra; D J Inwards; S M Ansell; I N Micallef; P B Johnston; W J Hogan; S N Markovic; L F Porrata
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3.  Lymphocyte recovery predicts outcomes in cord blood and T cell-depleted haploidentical stem cell transplantation.

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4.  Absolute Lymphocyte Count (ALC) after Induction Treatment Predicts Survival of Pediatric Patients with Acute Lymphoblastic Leukemia.

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5.  Autograft mediated adoptive immunotherapy of cancer in the context of autologous stem cell transplantation.

Authors:  Luis F Porrata; Svetomir N Markovic
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6.  Interleukin-15 affects patient survival through natural killer cell recovery after autologous hematopoietic stem cell transplantation for non-Hodgkin lymphomas.

Authors:  Luis F Porrata; David J Inwards; Ivana N Micallef; Patrick B Johnston; Stephen M Ansell; William J Hogan; Svetomir N Markovic
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Review 7.  Harnessing the effect of adoptively transferred tumor-reactive T cells on endogenous (host-derived) antitumor immunity.

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8.  The prognostic role of the preoperative absolute lymphocyte count and absolute monocyte count in patients with resected advanced melanoma.

Authors:  Nicole M Rochet; Lisa A Kottschade; Travis E Grotz; Luis F Porrata; Svetomir N Markovic
Journal:  Am J Clin Oncol       Date:  2015-06       Impact factor: 2.339

9.  Early lymphocyte recovery predicts superior survival after autologous stem cell transplantation in non-Hodgkin lymphoma: a prospective study.

Authors:  Luis F Porrata; David J Inwards; Stephen M Ansell; Ivana N Micallef; Patrick B Johnston; Dennis A Gastineau; Mark R Litzow; Jeffrey L Winters; Svetomir N Markovic
Journal:  Biol Blood Marrow Transplant       Date:  2008-07       Impact factor: 5.742

10.  Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy.

Authors:  Claude Sportès; Rebecca R Babb; Michael C Krumlauf; Frances T Hakim; Seth M Steinberg; Catherine K Chow; Margaret R Brown; Thomas A Fleisher; Pierre Noel; Irina Maric; Maryalice Stetler-Stevenson; Julie Engel; Renaud Buffet; Michel Morre; Robert J Amato; Andrew Pecora; Crystal L Mackall; Ronald E Gress
Journal:  Clin Cancer Res       Date:  2010-01-12       Impact factor: 12.531
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