Literature DB >> 12027861

Tachycardia and convulsions induced by accidental intravascular ropivacaine injection during sciatic block.

F Petitjeans1, G Mion, M Puidupin, J P Tourtier, C Hutson, J M Saissy.   

Abstract

Ropivacaine, a recently introduced local anesthetic of the amide family (1), seems to show less toxicity than bupivacaine (2-4). Nevertheless, both neurologic and cardiovascular toxicities are possible. Six cases of ropivacaine-induced convulsions have previously been reported (5-10), of which three cases also showed cardiovascular toxicity. In three cases, total plasma concentrations were measured (Table 1).

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Year:  2002        PMID: 12027861     DOI: 10.1034/j.1399-6576.2002.460524.x

Source DB:  PubMed          Journal:  Acta Anaesthesiol Scand        ISSN: 0001-5172            Impact factor:   2.105


  6 in total

Review 1.  [Toxicology of local anesthetics. Clinical, therapeutic and pathological mechanisms].

Authors:  W Zink; B M Graf
Journal:  Anaesthesist       Date:  2003-12       Impact factor: 1.041

2.  [Inadvertent intravenous infusion of 380 mg ropivacaine].

Authors:  G Pfeiffer; K Bär; P Neubauer; M Höhne
Journal:  Anaesthesist       Date:  2004-07       Impact factor: 1.041

Review 3.  Peripheral nerve blocks for perioperative management of patients having orthopedic surgery or trauma of the lower extremity.

Authors:  Takashige Iwata; Sundaram Lakshman; Alpana Singh; Marina Yufa; Rich Claudio; Admir Hadzić
Journal:  Bosn J Basic Med Sci       Date:  2005-05       Impact factor: 3.363

4.  A Comparison of Differences Between the Systemic Pharmacokinetics of Levobupivacaine and Ropivacaine During Continuous Epidural Infusion: A Prospective, Randomized, Multicenter, Double-Blind Controlled Trial.

Authors:  Luciano Perotti; Maria Cusato; Pablo Ingelmo; Thekla Larissa Niebel; Marta Somaini; Francesca Riva; Carmine Tinelli; José De Andrés; Guido Fanelli; Antonio Braschi; Mario Regazzi; Massimo Allegri
Journal:  Anesth Analg       Date:  2015-08       Impact factor: 5.108

5.  Acute Cervical Subdural Hematoma with Quadriparesis after Cervical Transforaminal Epidural Block.

Authors:  Jun Kyu Lee; Ki Whan Chae; Chang Il Ju; Byoung Wook Kim
Journal:  J Korean Neurosurg Soc       Date:  2015-11-30

6.  Population pharmacokinetics of bupivacaine in combined lumbar and sciatic nerve block.

Authors:  Hanene Eljebari; Nadia Jebabli; Issam Salouage; Emna Gaies; Mohamed Lakhal; Mehdi Boussofara; Anis Klouz
Journal:  Indian J Pharmacol       Date:  2014 Mar-Apr       Impact factor: 1.200

  6 in total

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