Literature DB >> 12027748

Antiangiogenic activity of synthetic dihydrobenzofuran lignans.

Sandra Apers1, Dietrich Paper, Jutta Bürgermeister, Slavka Baronikova, Stefaan Van Dyck, Guy Lemière, Arnold Vlietinck, Luc Pieters.   

Abstract

A series of synthetic dihydrobenzofuran lignans, obtained by biomimetic oxidative dimerization of caffeic or ferulic acid methyl ester followed by derivatization reactions, was tested for its antiangiogenic activity in the CAM (chorioallantoic membrane) assay. The dimerization product of caffeic acid methyl ester (2a) (methyl (E)-3-[2-(3,4-dihydroxyphenyl)-7-hydroxy-3-methoxycarbonyl-2,3-dihydro-1-benzofuran-5-yl]prop-2-enoate) showed a pronounced antiangiogenic activity, especially the 2R,3R-enantiomer.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12027748     DOI： 10.1021/np0103968

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

1.  Antiangiogenic properties of an unusual benzo[k,l]xanthene lignan derived from CAPE (caffeic acid phenethyl ester).

Authors:  Giuseppina Basini; Laura Baioni; Simona Bussolati; Francesca Grasselli; Carmelo Daquino; Carmela Spatafora; Corrado Tringali
Journal:  Invest New Drugs       Date:  2010-10-06       Impact factor: 3.850

2.  Novel derivative of benzofuran induces cell death mostly by G2/M cell cycle arrest through p53-dependent pathway but partially by inhibition of NF-kappaB.

Authors:  Sunil K Manna; Julie S Bose; Vijay Gangan; Nune Raviprakash; Thota Navaneetha; Pongali B Raghavendra; Banaganapalli Babajan; Chitta S Kumar; Swatantra K Jain
Journal:  J Biol Chem       Date:  2010-05-14       Impact factor: 5.157

3.  Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis.

Authors:  Shu-Yi Yin; Feng-Yin Jian; Yung-Hsiang Chen; Shih-Chang Chien; Mao-Chih Hsieh; Pei-Wen Hsiao; Wen-Hwa Lee; Yueh-Hsiung Kuo; Ning-Sun Yang
Journal:  Nat Commun       Date:  2016-04-18       Impact factor: 14.919

4.  Enantioselective Catalytic [4+1]-Cyclization of ortho-Hydroxy-para-Quinone Methides with Allenoates.

Authors:  Katharina Zielke; Ondřej Kováč; Michael Winter; Jiří Pospíšil; Mario Waser
Journal:  Chemistry       Date:  2019-05-21       Impact factor: 5.236

5.  AAPH or Peroxynitrite-Induced Biorelevant Oxidation of Methyl Caffeate Yields a Potent Antitumor Metabolite.

Authors:  Laura Fási; Ahmed Dhahir Latif; István Zupkó; Sándor Lévai; Miklós Dékány; Zoltán Béni; Árpád Könczöl; György Tibor Balogh; Attila Hunyadi
Journal:  Biomolecules       Date:  2020-11-11

Review 6.  Caffeic acid phenethyl ester as a remedial agent for reproductive functions and oxidative stress-based pathologies of gonads.

Authors:  Sumeyya Akyol; Ali Akbas; Ilknur Butun; Muhsin Toktas; Huseyin Ozyurt; Semsettin Sahin; Omer Akyol
Journal:  J Intercult Ethnopharmacol       Date:  2015-04-03

7.  Synthesis of New 2-Arylbenzo[b]furan Derivatives via Palladium-Catalyzed Suzuki Cross-Coupling Reactions in Aqueous Media.

Authors:  Qianqian Chen; Panli Jiang; Mengping Guo; Jianxin Yang
Journal:  Molecules       Date:  2018-09-25       Impact factor: 4.411
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.