Literature DB >> 12027738

Five new iboga alkaloids from Tabernaemontana corymbosa.

Toh-Seok Kam1, Kooi-Mow Sim.   

Abstract

Five new indole alkaloids of the ibogan type (1-5), in addition to 12 other known iboga alkaloids, were obtained from the leaf and stem-bark extract of the Malayan species Tabernaemontana corymbosa, viz., 19(S)-hydroxyibogamine (1), 19-epi-isovoacristine (2), isovoacryptine (3), 3R/S-ethoxyheyneanine (4), and 3R/S-ethoxy-19-epi-heyneanine (5). The structures were determined using NMR and MS analysis and comparison with known related compounds.

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Year:  2002        PMID: 12027738     DOI: 10.1021/np0105432

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

1.  Application of preparative high-speed counter-current chromatography for the separation of two alkaloids from the roots of Tabernaemontana catharinensis (Apocynaceae).

Authors:  Milena S Gonçalves; Ivo J Curcino Vieira; Rodrigo R Oliveira; Raimundo Braz-Filho
Journal:  Molecules       Date:  2011-09-02       Impact factor: 4.411

2.  Acaricidal activity of the aqueous and hydroethanolic extracts of 15 South African plants against Rhipicephalus turanicus and their toxicity on human liver and kidney cells.

Authors:  Gerda Fouche; Olubukola T Adenubi; Tlabo Leboho; Lyndy J McGaw; Vinny Naidoo; Kevin W Wellington; Jacobus N Eloff
Journal:  Onderstepoort J Vet Res       Date:  2019-07-22       Impact factor: 1.792

3.  New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata.

Authors:  Xiang-Mei Li; Xian-Jun Jiang; Guo-Zhu Wei; Li-Hua Ren; Li-Xia Wang; Xue-Lian Cheng; Fei Wang
Journal:  Nat Prod Bioprospect       Date:  2019-11-14

Review 4.  Chemical Diversity and Bioactivities of Monoterpene Indole Alkaloids (MIAs) from Six Apocynaceae Genera.

Authors:  Afrah E Mohammed; Zainab H Abdul-Hameed; Modhi O Alotaibi; Nahed O Bawakid; Tariq R Sobahi; Ahmed Abdel-Lateff; Walied M Alarif
Journal:  Molecules       Date:  2021-01-18       Impact factor: 4.411

Review 5.  Major Bioactive Alkaloids and Biological Activities of Tabernaemontana Species (Apocynaceae).

Authors:  Clarissa Marcelle Naidoo; Yougasphree Naidoo; Yaser Hassan Dewir; Hosakatte Niranjana Murthy; Salah El-Hendawy; Nasser Al-Suhaibani
Journal:  Plants (Basel)       Date:  2021-02-05

6.  Cytotoxicity and genotoxicity of coronaridine from Tabernaemontana catharinensis A.DC in a human laryngeal epithelial carcinoma cell line (Hep-2).

Authors:  Walace Fraga Rizo; Luis Eduardo Ferreira; Vanessa Colnaghi; Juliana Simões Martins; Leonardo Pereira Franchi; Catarina Satie Takahashi; Rene Oliveira Beleboni; Mozart Marins; Paulo Sérgio Pereira; Ana Lúcia Fachin
Journal:  Genet Mol Biol       Date:  2013-03-04       Impact factor: 1.771

  6 in total

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