| Literature DB >> 12027637 |
Mark Lautens1, John T Colucci, Sheldon Hiebert, Nicholas D Smith, Giliane Bouchain.
Abstract
[structure: see text] The total synthesis of the polyether antibiotic ionomycin, a calcium ionophore, is described. The synthesis demonstrates the utility of ring-opening methodologies as applied to the synthesis of polypropionate and deoxypolypropionate subunits, which are found in two of the four fragments in the synthesis.Entities:
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Year: 2002 PMID： 12027637 DOI： 10.1021/ol025872f
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005