Literature DB >> 1202699

[Specific substances of the thymus reacting with thymus-dependant antigens].

I A Bezvershenko, L M Bykova, R H Lukashova.   

Abstract

A fraction was isolated from the sulphate extract of rats and calfs thymus. This fraction reacts with sheep erythrocytes and rabbits IgG in the agglutination test. An identical fraction from the rats spleen and liver is not active in the same concentration. Active substance was purified by affinity chromatography on IgG cellulose column. The absorption spectrum of the purified substance in 220-300 nm region was studied at pH 7. This substance has not the absorption maxima in 280 nm. The sedimentation constant of the crude preparation is approximately 1.7 s. It supposed, that this substance is a specifical receptor of thymic cells.

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Year:  1975        PMID: 1202699

Source DB:  PubMed          Journal:  Ukr Biokhim Zh


  1 in total

1.  The substance reacting with SRBC (sheep red blood cells) and rabbit IgG. Isolation under mild conditions from rat thymus.

Authors:  I A Bezvershenko; M G Boyko; L M Bykova
Journal:  Mol Biol Rep       Date:  1977-03       Impact factor: 2.316

  1 in total

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