Literature DB >> 12026011

Hamlet--a complex from human milk that induces apoptosis in tumor cells but spares healthy cells.

Malin Svensson1, Caroline Düringer, Oskar Hallgren, Ann-Kristine Mossberg, Anders Håkansson, Sara Linse, Catharina Svanborg.   

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Year:  2002        PMID： 12026011     DOI： 10.1007/978-1-4615-0559-4_14

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


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  12 in total

1.  Influence of pH on the structure and oleic acid binding ability of bovine α-lactalbumin.

Authors:  Bing Fang; Ming Zhang; Lu Jiang; Hao Jing; Fa Zheng Ren
Journal:  Protein J       Date:  2012-10       Impact factor: 2.371

2.  The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in Streptococcus pneumoniae.

Authors:  Hazeline Roche-Hakansson; Goutham Vansarla; Laura R Marks; Anders P Hakansson
Journal:  J Biol Chem       Date:  2019-11-06       Impact factor: 5.157

3.  A Protein Complex from Human Milk Enhances the Activity of Antibiotics and Drugs against Mycobacterium tuberculosis.

Authors:  Virginia Meikle; Ann-Kristin Mossberg; Avishek Mitra; Anders P Hakansson; Michael Niederweis
Journal:  Antimicrob Agents Chemother       Date:  2019-01-29       Impact factor: 5.191

4.  Free Fatty Acid and α-Lactalbumin-Oleic Acid Complexes in Preterm Human Milk Are Cytotoxic to Fetal Intestinal Cells in vitro.

Authors:  Katherine E Chetta; Danforth A Newton; Carol L Wagner; John E Baatz
Journal:  Front Nutr       Date:  2022-07-05

Review 5.  Protein-lipid complexes: molecular structure, current scenarios and mechanisms of cytotoxicity.

Authors:  Esmail M El-Fakharany; Elrashdy M Redwan
Journal:  RSC Adv       Date:  2019-11-13       Impact factor: 4.036

6.  The Use of Human, Bovine, and Camel Milk Albumins in Anticancer Complexes with Oleic Acid.

Authors:  Esmail M El-Fakharany; Marwa M Abu-Serie; Ekaterina A Litus; Sergei E Permyakov; Eugene A Permyakov; Vladimir N Uversky; Elrashdy M Redwan
Journal:  Protein J       Date:  2018-06       Impact factor: 2.371

7.  Examination of the activity of camel milk casein against hepatitis C virus (genotype-4a) and its apoptotic potential in hepatoma and hela cell lines.

Authors:  Osama Almahdy; Esmail M El-Fakharany; Ehab El-Dabaa; Tzi Bun Ng; Elrashdy M Redwan
Journal:  Hepat Mon       Date:  2011-09       Impact factor: 0.660

8.  Lack of functional alpha-lactalbumin prevents involution in Cape fur seals and identifies the protein as an apoptotic milk factor in mammary gland involution.

Authors:  Julie A Sharp; Christophe Lefèvre; Kevin R Nicholas
Journal:  BMC Biol       Date:  2008-11-06       Impact factor: 7.431

9.  Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells.

Authors:  Y-B Zhang; J-L Gong; T-Y Xing; S-P Zheng; W Ding
Journal:  Cell Death Dis       Date:  2013-03-21       Impact factor: 8.469

10.  Low resolution solution structure of HAMLET and the importance of its alpha-domains in tumoricidal activity.

Authors:  C S James Ho; Anna Rydstrom; Malathy Sony Subramanian Manimekalai; Catharina Svanborg; Gerhard Grüber
Journal:  PLoS One       Date:  2012-12-27       Impact factor: 3.240
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