| Literature DB >> 12023408 |
M D Greicius1, M D Geschwind, B L Miller.
Abstract
The four major degenerative dementias that often begin in presenescence: are reviewed. These are Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, and Creutzfeldt-Jakob disease. Their epidemiological, genetic, and clinical features are reviewed, and controversies in taxonomy arising from recent discoveries described. Particular attention is given to the pathological role of protein aggregation, which appears to be a factor in each disease.Entities:
Mesh:
Year: 2002 PMID: 12023408 PMCID: PMC1737933 DOI: 10.1136/jnnp.72.6.691
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN: 0022-3050 Impact factor: 10.154