Literature DB >> 120234

An effective rabies treatment in exposed monkeys: a single dose of interferon inducer and vaccine.

G M Baer, S A Moore, J H Shaddock, H B Levy.   

Abstract

Rhesus monkeys were injected with lethal doses of rabies virus and then treated with a variety of treatment combinations. The one found most successful was one dose of an interferon inducer (poly(I)-poly(C) complexed to poly-L-lysine and carboxymethyl-cellulose) and one dose of human diploid rabies vaccine. This combination proved to be as effective as hyperimmune serum and vaccine, and much better than vaccine alone. The combination of the interferon inducer plus vaccine could be administered at least up to 48 hours after the very severe challenge given and still provide marked protection.

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Year:  1979        PMID： 120234      PMCID： PMC2395871     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN： 0042-9686            Impact factor:   9.408


  23 in total

1.  INCIDENCE OF REACTIONS FOLLOWING ADMINISTRATION OF ANTIRABIES SERUM; STUDY OF 526 CASES.

Authors:  J S KARLINER; G S BELAVAL
Journal:  JAMA       Date:  1965-08-02       Impact factor: 56.272

2.  Rabies neutralizing antibody response to different schedules of serum and vaccine inoculations in non-exposed persons. 3.

Authors:  P ATANASIU; D A CANNON; D J DEAN; J P FOX; K HABEL; M M KAPLAN; R E KISSLING; H KOPROWSKI; P LEPINE; F PEREZ GALLARDO
Journal:  Bull World Health Organ       Date:  1961       Impact factor: 9.408

3.  An Attenuated Rabies Vaccine for Domestic Animals Produced in Tissue Culture.

Authors:  M K Abelseth
Journal:  Can Vet J       Date:  1964-11       Impact factor: 1.008

4.  Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.

Authors:  I MACPHERSON; M STOKER
Journal:  Virology       Date:  1962-02       Impact factor: 3.616

5.  Comparative pathogenesis of rabies and rabies-like viruses. Viral infection and transit from inoculation site to the central nervous system.

Authors:  F A Murphy; S P Bauer; A K Harrison; W C Winn
Journal:  Lab Invest       Date:  1973-03       Impact factor: 5.662

6.  Successful protection of humans exposed to rabies infection. Postexposure treatment with the new human diploid cell rabies vaccine and antirabies serum.

Authors:  M Bahmanyar; A Fayaz; S Nour-Salehi; M Mohammadi; H Koprowski
Journal:  JAMA       Date:  1976-12-13       Impact factor: 56.272

7.  Therapy of murine rabies after exposure: efficacy of polyriboinosinic-polyribocytidylic acid alone and in combination with three rabies vaccines.

Authors:  M W Harmon; B Janis
Journal:  J Infect Dis       Date:  1975-09       Impact factor: 5.226

8.  Prevention of human rabies; treatment of persons bitten by rabid wolves in Iran.

Authors:  M BALTAZARD; M GHODSSI
Journal:  Bull World Health Organ       Date:  1954       Impact factor: 9.408

9.  Early street rabies virus infection in striated muscle and later progression to the central nervous system.

Authors:  F A Murphy; S P Bauer
Journal:  Intervirology       Date:  1974       Impact factor: 1.763

10.  Successful prophylaxis against rabies in mice and Rhesus monkeys: the interferon system and vaccine.

Authors:  G M Baer; J H Shaddock; S A Moore; P A Yager; S S Baron; H B Levy
Journal:  J Infect Dis       Date:  1977-08       Impact factor: 5.226
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  3 in total

1.  Comparison of human immune responses to purified Vero cell and human diploid cell rabies vaccines by using two different antibody titration methods.

Authors:  P M Kitala; K J Lindqvist; E Koimett; B K Johnson; C N Chunge; P Perrin; O Olsvik
Journal:  J Clin Microbiol       Date:  1990-08       Impact factor: 5.948

2.  Involvement of the rabies virus phosphoprotein gene in neuroinvasiveness.

Authors:  Satoko Yamaoka; Naoto Ito; Seii Ohka; Shohei Kaneda; Hiroko Nakamura; Takahiro Agari; Tatsunori Masatani; Keisuke Nakagawa; Kazuma Okada; Kota Okadera; Hiromichi Mitake; Teruo Fujii; Makoto Sugiyama
Journal:  J Virol       Date:  2013-09-11       Impact factor: 5.103

3.  Exogenous interferon prolongs survival of rabies infected mice.

Authors:  S Mehta; S Roy; S Mukherjee; N Yadav; N Patel; A Chowdhary
Journal:  Virusdisease       Date:  2015-08-14
  3 in total

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