Literature DB >> 12021384

ATP-sensitive K(+) channels in the brain: sensors of hypoxic conditions.

Katsuya Yamada1, Nobuya Inagaki.   

Abstract

Rapid minimization of energy consumption in excitable tissues is effective protection from lethal effects of extreme metabolic stress. The ATP-sensitive K(+) channels in the brain respond in ATP-depleted metabolic states such as hypoxia and may be involved in the protection mechanism against energy-consuming generalized seizure.

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Year:  2002        PMID： 12021384     DOI： 10.1152/nips.01384.2001

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  5 in total

1.  The protective effect of epoxyeicosatrienoic acids on cerebral ischemia/reperfusion injury is associated with PI3K/Akt pathway and ATP-sensitive potassium channels.

Authors:  You-Yang Qu; Mei-Yan Yuan; Yu Liu; Xing-Jun Xiao; Yu-Lan Zhu
Journal:  Neurochem Res       Date:  2014-11-04       Impact factor: 3.996

2.  Characterization of an ATP-sensitive K(+) channel in rat carotid body glomus cells.

Authors:  Donghee Kim; Insook Kim; Justin R Papreck; David F Donnelly; John L Carroll
Journal:  Respir Physiol Neurobiol       Date:  2011-04-22       Impact factor: 1.931

3.  The effects induced by the sulphonylurea glibenclamide on the neonatal rat spinal cord indicate a novel mechanism to control neuronal excitability and inhibitory neurotransmission.

Authors:  K Ostroumov; M Grandolfo; A Nistri
Journal:  Br J Pharmacol       Date:  2006-11-27       Impact factor: 8.739

4.  Ischemic postconditioning prevents surge of presynaptic glutamate release by activating mitochondrial ATP-dependent potassium channels in the mouse hippocampus.

Authors:  Shohei Yokoyama; Ichiro Nakagawa; Yoichi Ogawa; Yudai Morisaki; Yasushi Motoyama; Young Su Park; Yasuhiko Saito; Hiroyuki Nakase
Journal:  PLoS One       Date:  2019-04-12       Impact factor: 3.240

5.  Hypoxia antagonizes glucose deprivation on interleukin 6 expression in an Akt dependent, but HIF-1/2α independent manner.

Authors:  Sung Ji Choi; Ik Jae Shin; Kang-Hoon Je; Eun Kyoung Min; Eun Ji Kim; Hee-Sun Kim; Senyon Choe; Dong-Eog Kim; Dong Kun Lee
Journal:  PLoS One       Date:  2013-03-08       Impact factor: 3.240
  5 in total

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