Literature DB >> 12021000

Mechanical behavior of coronary stents investigated through the finite element method.

Francesco Migliavacca1, Lorenza Petrini, Maurizio Colombo, Ferdinando Auricchio, Riccardo Pietrabissa.   

Abstract

Intravascular stents are small tube-like structures expanded into stenotic arteries to restore blood flow perfusion to the downstream tissues. The stent is mounted on a balloon catheter and delivered to the site of blockage. When the balloon is inflated, the stent expands and is pressed against the inner wall of the coronary artery. After the balloon is deflated and removed, the stent remains in place, keeping the artery open. Hence, the stent expansion defines the effectiveness of the surgical procedure: it depends on the stent geometry, it includes large displacements and deformations and material non-linearity. In this paper, the finite element method is applied (i) to understand the effects of different geometrical parameters (thickness, metal-to-artery surface ratio, longitudinal and radial cut lengths) of a typical diamond-shaped coronary stent on the device mechanical performance, (ii) to compare the response of different actual stent models when loaded by internal pressure and (iii) to collect suggestions for optimizing the device shape and performance. The stent expansion and partial recoil under balloon inflation and deflation were simulated. Results showed the influence of the geometry on the stent behavior: a stent with a low metal-to-artery surface ratio has a higher radial and longitudinal recoil, but a lower dogboning. The thickness influences the stent performance in terms of foreshortening, longitudinal recoil and dogboning. In conclusion, a finite element analysis similar to the one herewith proposed could help in designing new stents or analyzing actual stents to ensure ideal expansion and structural integrity, substituting in vitro experiments often difficult and unpractical.

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Year:  2002        PMID: 12021000     DOI: 10.1016/s0021-9290(02)00033-7

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  21 in total

1.  Mechanical behavior of fully expanded commercially available endovascular coronary stents.

Authors:  Josip Tambaca; Suncica Canic; Mate Kosor; R David Fish; David Paniagua
Journal:  Tex Heart Inst J       Date:  2011

2.  Three-dimensional numerical simulations of physiological flows in a stented coronary bifurcation.

Authors:  V Deplano; C Bertolotti; P Barragan
Journal:  Med Biol Eng Comput       Date:  2004-09       Impact factor: 2.602

3.  Determination of the influence of stent strut thickness using the finite element method: implications for vascular injury and in-stent restenosis.

Authors:  Houman Zahedmanesh; Caitríona Lally
Journal:  Med Biol Eng Comput       Date:  2009-02-03       Impact factor: 2.602

Review 4.  Patient-specific modeling of cardiovascular mechanics.

Authors:  C A Taylor; C A Figueroa
Journal:  Annu Rev Biomed Eng       Date:  2009       Impact factor: 9.590

Review 5.  Mechanoresponsive materials for drug delivery: Harnessing forces for controlled release.

Authors:  Julia Wang; Jonah A Kaplan; Yolonda L Colson; Mark W Grinstaff
Journal:  Adv Drug Deliv Rev       Date:  2016-11-14       Impact factor: 15.470

6.  Evaluation of the effect of expansion and shear stress on a self-assembled endothelium mimicking nanomatrix coating for drug eluting stents in vitro and in vivo.

Authors:  Adinarayana Andukuri; IlJae Min; Patrick Hwang; Grant Alexander; Lauren E Marshall; Joel L Berry; Timothy M Wick; Yoon Ki Joung; Young-Sup Yoon; Brigitta C Brott; Dong Keun Han; Ho-Wook Jun
Journal:  Biofabrication       Date:  2014-07-22       Impact factor: 9.954

7.  Plastic strains during stent deployment have a critical influence on the rate of corrosion in absorbable magnesium stents.

Authors:  Emmet Galvin; Christy Cummins; Shoichiro Yoshihara; Bryan J Mac Donald; Caitríona Lally
Journal:  Med Biol Eng Comput       Date:  2016-10-26       Impact factor: 2.602

Review 8.  Biomaterial-Based Approaches to Address Vein Graft and Hemodialysis Access Failures.

Authors:  Timothy C Boire; Daniel A Balikov; Yunki Lee; Christy M Guth; Joyce Cheung-Flynn; Hak-Joon Sung
Journal:  Macromol Rapid Commun       Date:  2016-09-27       Impact factor: 5.734

9.  Mechanical modeling of stents deployed in tapered arteries.

Authors:  Lucas H Timmins; Clark A Meyer; Michael R Moreno; James E Moore
Journal:  Ann Biomed Eng       Date:  2008-10-10       Impact factor: 3.934

10.  The effects of clinically-derived parametric data uncertainty in patient-specific coronary simulations with deformable walls.

Authors:  Jongmin Seo; Daniele E Schiavazzi; Andrew M Kahn; Alison L Marsden
Journal:  Int J Numer Method Biomed Eng       Date:  2020-06-25       Impact factor: 2.747

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