OBJECTIVE: To investigate the association between dietary carotenoid intake and lung cancer risk in women. METHODS: A case-cohort study was undertaken in the Canadian National Breast Screening Study dietary cohort, which consists of 56,837 women who completed a self-administered dietary questionnaire. The cohort was recruited between 1980 and 1985, and during follow-up to the end of 1993 a total of 196 cohort members were diagnosed with incident lung cancer. For analysis, a subcohort consisting of a random sample of 5681 women was selected from the full dietary cohort. After exclusions for various reasons, the analyses were based on 155 cases and 5,361 non-cases. RESULTS: When compared to those in the lowest quartile level of intake, the adjusted incidence rate ratios (95% confidence intervals) for those in the highest quartile levels of alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, and lutein intake were 0.90 (0.51-1.58). 1.40 (0.76-2.59), 0.66 (0.33-1.32), 1.04 (0.61-1.76), and 1.26 (0.70-2.24), respectively; none of the associated tests for trend was statistically significant. CONCLUSION: These results suggest that there is no association between dietary carotenoid intake and lung cancer risk. at least for the range of intakes observed here.
OBJECTIVE: To investigate the association between dietary carotenoid intake and lung cancer risk in women. METHODS: A case-cohort study was undertaken in the Canadian National Breast Screening Study dietary cohort, which consists of 56,837 women who completed a self-administered dietary questionnaire. The cohort was recruited between 1980 and 1985, and during follow-up to the end of 1993 a total of 196 cohort members were diagnosed with incident lung cancer. For analysis, a subcohort consisting of a random sample of 5681 women was selected from the full dietary cohort. After exclusions for various reasons, the analyses were based on 155 cases and 5,361 non-cases. RESULTS: When compared to those in the lowest quartile level of intake, the adjusted incidence rate ratios (95% confidence intervals) for those in the highest quartile levels of alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, and lutein intake were 0.90 (0.51-1.58). 1.40 (0.76-2.59), 0.66 (0.33-1.32), 1.04 (0.61-1.76), and 1.26 (0.70-2.24), respectively; none of the associated tests for trend was statistically significant. CONCLUSION: These results suggest that there is no association between dietary carotenoid intake and lung cancer risk. at least for the range of intakes observed here.
Authors: G Sowmya Shree; K Yogendra Prasad; H S Arpitha; U R Deepika; K Nawneet Kumar; Priya Mondal; P Ganesan Journal: Mol Cell Biochem Date: 2017-05-26 Impact factor: 3.396
Authors: Jessie A Satia; Alyson Littman; Christopher G Slatore; Joseph A Galanko; Emily White Journal: Am J Epidemiol Date: 2009-02-10 Impact factor: 4.897
Authors: Jung Eun Lee; Donna Spiegelman; David J Hunter; Demetrius Albanes; Leslie Bernstein; Piet A van den Brandt; Julie E Buring; Eunyoung Cho; Dallas R English; Jo L Freudenheim; Graham G Giles; Saxon Graham; Pamela L Horn-Ross; Niclas Håkansson; Michael F Leitzmann; Satu Männistö; Marjorie L McCullough; Anthony B Miller; Alexander S Parker; Thomas E Rohan; Arthur Schatzkin; Leo J Schouten; Carol Sweeney; Walter C Willett; Alicja Wolk; Shumin M Zhang; Stephanie A Smith-Warner Journal: J Natl Cancer Inst Date: 2008-11-25 Impact factor: 13.506
Authors: Jung Eun Lee; Satu Männistö; Donna Spiegelman; David J Hunter; Leslie Bernstein; Piet A van den Brandt; Julie E Buring; Eunyoung Cho; Dallas R English; Andrew Flood; Jo L Freudenheim; Graham G Giles; Edward Giovannucci; Niclas Håkansson; Pamela L Horn-Ross; Eric J Jacobs; Michael F Leitzmann; James R Marshall; Marjorie L McCullough; Anthony B Miller; Thomas E Rohan; Julie A Ross; Arthur Schatzkin; Leo J Schouten; Jarmo Virtamo; Alicja Wolk; Shumin M Zhang; Stephanie A Smith-Warner Journal: Cancer Epidemiol Biomarkers Prev Date: 2009-06 Impact factor: 4.254