Literature DB >> 120201

Postnatal development of uridine diphosphate glucuronyltransferase activity towards bilirubin and 2-aminophenol in human liver.

S Onishi, N Kawade, S Itoh, K Isobe, S Sugiyama.   

Abstract

UDP-glucuronyltransferase activities towards 2-aminophenol and bilirubin were studied in a total of 70 human subjects, including premature and full-term newborn babies, infants, children and adults. These two activities have been reported in rat to develop latefoetally and neonatally respectively, but in man they both develop neonatally. There is a linear relationship between the logarithm of each liver transferase activity and the logarithm of the number of days after birth during the first 3 months of life, after which each activity remains constant.

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Year:  1979        PMID： 120201      PMCID： PMC1161858          DOI： 10.1042/bj1840705

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  13 in total

1.  Demonstration of functional heterogeneity of hepatic uridine diphosphate glucuronosyltransferase activities after administration of 3-methylcholanthrene and phenobarbital to rats.

Authors:  G J Wishart
Journal:  Biochem J       Date:  1978-08-15       Impact factor: 3.857

2.  Functional heterogeneity of UDP-glucuronosyltransferase as indicated by its differential development and inducibility by glucocorticoids. Demonstration of two groups within the enzyme's activity towards twelve substrates.

Authors:  G J Wishart
Journal:  Biochem J       Date:  1978-08-15       Impact factor: 3.857

3.  SOME PROBLEMS IN EXPRESSING AND COMPARING BODY COMPOSITION DETERMINED BY DIRECT ANALYSIS.

Authors:  I MILLER; W B WEIL
Journal:  Ann N Y Acad Sci       Date:  1963-09-26       Impact factor: 5.691

4.  Recent advances in the separation and analysis of diazo-positive bile pigments.

Authors:  K P Heirwegh; J Fevery; J A Meuwissen; J De Groote; F Compernolle; V Desmet; F P Van Roy
Journal:  Methods Biochem Anal       Date:  1974

5.  Animal model of human disease. Crigler-Najjar Syndrome. Animal model: hereditary nonhemolytic unconjugated hyperbilirubinemia in Gunn rats.

Authors:  C E Cornelius; I M Arias
Journal:  Am J Pathol       Date:  1972-11       Impact factor: 4.307

Review 6.  Critique of the assay and significance of bilirubin conjugation.

Authors:  K P Heirwegh; J A Meuwissen; J Fevery
Journal:  Adv Clin Chem       Date:  1973       Impact factor: 5.394

7.  Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.

Authors:  K W Bock; W Fröhling; H Remmer; B Rexer
Journal:  Biochim Biophys Acta       Date:  1973-11-15

8.  Demonstration of two functionally heterogenous groups within the activities of UDP-glucuronosyltransferase towards a series of 4-alkyl-substituted phenols.

Authors:  G J Wishart; M T Campbell
Journal:  Biochem J       Date:  1979-02-15       Impact factor: 3.857

9.  Steroid and non-steroid UDP glucuronyltransferase: glucuronidation of synthetic estrogens as steroids.

Authors:  G W Lucier; O S McDaniel
Journal:  J Steroid Biochem       Date:  1977-08       Impact factor: 4.292

10.  Unconjugated bilirubin and an increased proportion of bilirubin monoconjugates in the bile of patients with Gilbert's syndrome and Crigler-Najjar disease.

Authors:  J Fevery; N Blanckaert; K P Heirwegh; A M Préaux; P Berthelot
Journal:  J Clin Invest       Date:  1977-11       Impact factor: 14.808
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  34 in total

Review 1.  Glucuronidation in humans. Pharmacogenetic and developmental aspects.

Authors:  S N de Wildt; G L Kearns; J S Leeder; J N van den Anker
Journal:  Clin Pharmacokinet       Date:  1999-06       Impact factor: 6.447

2.  Uridine 5'-diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta.

Authors:  M Cappiello; L Giuliani; A Rane; G M Pacifici
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2000 Jul-Dec       Impact factor: 2.441

3.  Bilirubin uridine diphosphate-glucuronosyltransferase variation is a genetic basis of breast milk jaundice.

Authors:  Yoshihiro Maruo; Yoriko Morioka; Hiroshi Fujito; Sayuri Nakahara; Takahide Yanagi; Katsuyuki Matsui; Asami Mori; Hiroshi Sato; Robert H Tukey; Yoshihiro Takeuchi
Journal:  J Pediatr       Date:  2014-03-17       Impact factor: 4.406

4.  Antiretroviral Drugs in Meconium: Detection for Different Gestational Periods of Exposure.

Authors:  Sarah K Himes; Katherine Tassiopoulos; Ram Yogev; Marilyn A Huestis
Journal:  J Pediatr       Date:  2015-05-19       Impact factor: 4.406

5.  Meconium Atazanavir Concentrations and Early Language Outcomes in HIV-Exposed Uninfected Infants With Prenatal Atazanavir Exposure.

Authors:  Sarah K Himes; Yanling Huo; George K Siberry; Paige L Williams; Mabel L Rice; Patricia A Sirois; Toni Frederick; Rohan Hazra; Marilyn A Huestis
Journal:  J Acquir Immune Defic Syndr       Date:  2015-06-01       Impact factor: 3.731

6.  Validation of a novel method to identify in utero ethanol exposure: simultaneous meconium extraction of fatty acid ethyl esters, ethyl glucuronide, and ethyl sulfate followed by LC-MS/MS quantification.

Authors:  Sarah K Himes; Marta Concheiro; Karl B Scheidweiler; Marilyn A Huestis
Journal:  Anal Bioanal Chem       Date:  2014-01-10       Impact factor: 4.142

7.  Natural history of early neonatal bilirubinemia: a global perspective.

Authors:  Michael Kaplan; M Jeffrey Maisels
Journal:  J Perinatol       Date:  2021-01-04       Impact factor: 2.521

8.  Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia.

Authors:  Ryoichi Fujiwara; Shujuan Chen; Michael Karin; Robert H Tukey
Journal:  Gastroenterology       Date:  2011-10-06       Impact factor: 22.682

9.  Differential localisation of UDP-glucuronosyltransferase in kidney during human embryonic and fetal development.

Authors:  R Hume; M W Coughtrie; B Burchell
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

Review 10.  Ontogeny of hepatic and renal systemic clearance pathways in infants: part I.

Authors:  Jane Alcorn; Patrick J McNamara
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447
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