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Literature DB >> 12019127

Activities of therapeutic agents and myristamidopropyl dimethylamine against Acanthamoeba isolates.

Simon Kilvington¹, Reanne Hughes, James Byas, John Dart.

Abstract

The activities of therapeutic agents and myristamidopropyl dimethylamine (MAPD) against Acanthamoeba strains recalcitrant to medical therapy were studied. MAPD minimum cysticidal concentrations were 6.25 to 25 microg/ml; 10 to 30 microg/ml gave at least a 3-log cyst kill after 6 h, and 50 and 100 microg/ml gave at least a 3-log cyst kill within 2 and 1 h, respectively.

Entities: Chemical

Mesh：

Substances：

Year: 2002 PMID： 12019127 PMCID： PMC127201 DOI： 10.1128/AAC.46.6.2007-2009.2002

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

15 in total

1. Amoebicidal activity of a preserved contact lens multipurpose disinfecting solution compared to a disinfection/neutralisation peroxide system.

Authors: S L Buck; R A Rosenthal; R L Abshire
Journal: Cont Lens Anterior Eye Date: 1998 Impact factor: 3.077

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Authors: A S Bacon; D G Frazer; J K Dart; M Matheson; L A Ficker; P Wright
Journal: Eye (Lond) Date: 1993 Impact factor: 3.775

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Journal: Br J Ophthalmol Date: 1985-10 Impact factor: 4.638

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Authors: D F Larkin; S Kilvington; J K Dart
Journal: Ophthalmology Date: 1992-02 Impact factor: 12.079

5. Oral itraconazole and topical miconazole with débridement for Acanthamoeba keratitis.

Authors: Y Ishibashi; Y Matsumoto; T Kabata; R Watanabe; S Hommura; K Yasuraoka; K Ishii
Journal: Am J Ophthalmol Date: 1990-02-15 Impact factor: 5.258

6. Outcome of acanthamoeba keratitis treated with polyhexamethyl biguanide and propamidine.

Authors: I G Duguid; J K Dart; N Morlet; B D Allan; M Matheson; L Ficker; S Tuft
Journal: Ophthalmology Date: 1997-10 Impact factor: 12.079

7. Successful medical therapy of Acanthamoeba keratitis with topical chlorhexidine and propamidine.

Authors: D Seal; J Hay; C Kirkness; A Morrell; A Booth; A Tullo; A Ridgway; M Armstrong
Journal: Eye (Lond) Date: 1996 Impact factor: 3.775

8. Acanthamoeba keratitis in New Zealand, including two cases with in vivo resistance to polyhexamethylene biguanide.

Authors: D Murdoch; T B Gray; R Cursons; D Parr
Journal: Aust N Z J Ophthalmol Date: 1998-08

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Authors: J A Chawner; P Gilbert
Journal: J Appl Bacteriol Date: 1989-03

10. A clinicopathologic study of in vitro sensitivity testing and Acanthamoeba keratitis.

Authors: M J Elder; S Kilvington; J K Dart
Journal: Invest Ophthalmol Vis Sci Date: 1994-03 Impact factor: 4.799

6 in total

1. Practice patterns and opinions in the treatment of acanthamoeba keratitis.

Authors: Catherine E Oldenburg; Nisha R Acharya; Elmer Y Tu; Michael E Zegans; Mark J Mannis; Bruce D Gaynor; John P Whitcher; Thomas M Lietman; Jeremy D Keenan
Journal: Cornea Date: 2011-12 Impact factor: 2.651

2. In vitro amoebicidal activity of four Allium species on Acanthamoeba castellanii and their cytotoxic potentials on corneal cells.

Authors: Zubeyde Akin Polat; Ayse Vural; Bektas Tepe; Ali Cetin
Journal: Parasitol Res Date: 2007-02-22 Impact factor: 2.289

3. Acanthamoeba polyphaga strain age and method of cyst production influence the observed efficacy of therapeutic agents and contact lens disinfectants.

Authors: Reanne Hughes; Wayne Heaselgrave; Simon Kilvington
Journal: Antimicrob Agents Chemother Date: 2003-10 Impact factor: 5.191