| Literature DB >> 12018404 |
Christina A Mitchell1, Rajendra Gurung, Anne M Kong, Jennifer M Dyson, April Tan, Lisa M Ooms.
Abstract
Recent studies have identified the inositol polyphosphate 5-phosphatases as a large family of signal modifying enzymes comprising 10 mammalian and 4 yeast family members. A number of investigations including gene-targeted deletion of 5-phosphatases in mice have demonstrated that these enzymes regulate many important cellular events including hematopoietic cell proliferation and activation, insulin signaling, endocytosis, and actin polymerization.Entities:
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Year: 2002 PMID: 12018404 DOI: 10.1080/15216540210815
Source DB: PubMed Journal: IUBMB Life ISSN: 1521-6543 Impact factor: 3.885