Literature DB >> 12018026

Quantitative determination for cytotoxic Friedo-nor-oleanane derivatives from five morphological types of Maytenus ilicifolia (Celastraceae) by reverse-phase high-performance liquid chromatography.

Waldemar Buffa Filho1, Joaquim Corsino, da Silva Vanderlan Bolzani, Maysa Furlan, Ana Maria S Pereira, Suzelei Castro França.   

Abstract

Five different morphological types of Maytenus ilicifolia of the same age and harvested under the same conditions showed distinct accumulations of some friedo-nor-oleananes. A rapid, sensitive and reliable reverse-phase HPLC method (employing an external standard) was used for the determination of the cytotoxic triterpenoids, 20 alpha-hydroxymaytenin, 22 beta-hydroxymaytenin, maytenin, celastrol and pristimerin in each of the five types. Well resolved peaks with good detection response and linearity in the range 1.0-100 micrograms/mL were obtained.

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Year:  2002        PMID： 12018026     DOI： 10.1002/pca.626

Source DB:  PubMed          Journal:  Phytochem Anal        ISSN： 0958-0344            Impact factor:   3.373


  9 in total

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  9 in total

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