Literature DB >> 12015958

Cyclin G: a regulator of the p53-Mdm2 network.

Xinbin Chen1.   

Abstract

A recent study published in the April issue of Molecular Cell has shown that cyclin G, a p53 target, is a regulatory component of the active PP2A holoenzyme, which activates Mdm2 through dephosphorylation. These findings suggest that cyclin G is a key regulator of the p53-Mdm2 network.

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Year:  2002        PMID： 12015958     DOI： 10.1016/s1534-5807(02)00182-x

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  11 in total

1.  Lysine-independent turnover of cyclin G1 can be stabilized by B'alpha subunits of protein phosphatase 2A.

Authors:  Hongyun Li; Koji Okamoto; Melissa J Peart; Carol Prives
Journal:  Mol Cell Biol       Date:  2008-11-03       Impact factor: 4.272

2.  Essential amino acid supplementation alters the p53 transcriptional response and cytokine gene expression following total knee arthroplasty.

Authors:  Jonathan B Muyskens; Ari Winbush; Douglas M Foote; Douglas W Turnbull; Hans C Dreyer
Journal:  J Appl Physiol (1985)       Date:  2020-09-03

3.  Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. II. Gene array analysis reveals adaptive changes in cell cycle and cell death pathways.

Authors:  Sarah N Campion; E Andres Houseman; Moses A Sandrof; Janan B Hensley; Yunxia Sui; Kevin W Gaido; Zhijin Wu; Kim Boekelheide
Journal:  Toxicol Sci       Date:  2010-07-08       Impact factor: 4.849

4.  Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis.

Authors:  Paola Dongiovanni; Anna Ludovica Fracanzani; Gaetano Cairo; Chiara Paola Megazzini; Stefano Gatti; Raffaela Rametta; Silvia Fargion; Luca Valenti
Journal:  Am J Pathol       Date:  2009-12-17       Impact factor: 4.307

5.  Proteomic analysis of prolactinoma cells by immuno-laser capture microdissection combined with online two-dimensional nano-scale liquid chromatography/mass spectrometry.

Authors:  Yingchao Liu; Jinsong Wu; Guoquan Yan; Ruiping Hou; Dongxiao Zhuang; Luping Chen; Qi Pang; Jianhong Zhu
Journal:  Proteome Sci       Date:  2010-01-29       Impact factor: 2.480

6.  The Many Faces of MDM2 Binding Partners.

Authors:  Maurisa F Riley; Guillermina Lozano
Journal:  Genes Cancer       Date:  2012-03

7.  p53 and cyclin G cooperate in mediating genome stability in somatic cells of Drosophila.

Authors:  Fabienne E Bayer; Mirjam Zimmermann; Patrick Fischer; Christian Gromoll; Anette Preiss; Anja C Nagel
Journal:  Sci Rep       Date:  2017-12-20       Impact factor: 4.379

8.  LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis.

Authors:  Jiyoung Kim; Ji Heon Noh; Seung-Kyu Lee; Rachel Munk; Alexei Sharov; Elin Lehrmann; Yongqing Zhang; Weidong Wang; Kotb Abdelmohsen; Myriam Gorospe
Journal:  Oncotarget       Date:  2017-07-25

9.  Tumor protein p53 mutation in archived tumor samples from a 12-year survivor of stage 4 pancreatic ductal adenocarcinoma may predict long-term survival with DeltaRex-G: A case report and literature review.

Authors:  Michael A Morse; Sant P Chawla; Terence Z Wong; Howard W Bruckner; Frederick L Hall; Erlinda M Gordon
Journal:  Mol Clin Oncol       Date:  2021-07-08

10.  A genome-wide expression analysis identifies a network of EpCAM-induced cell cycle regulators.

Authors:  K Maaser; J Borlak
Journal:  Br J Cancer       Date:  2008-10-28       Impact factor: 7.640
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