Literature DB >> 1201569

Ventricular fibrillation threshold and vulnerable period in the isolated perfused rat heart.

W F Lubbe, O L Bricknell, C Marzagao.   

Abstract

Ventricular fibrillation threshold (VFT) measurements were obtained in the isolated perfused rat heart. Detailed morphology of the vulnerable period (VP) could be described by stimulating repeatedly at increasing levels of stimulus energy. Addition of lignocaine to the system caused an elevation of VGT, but also led to a delay of the VP to the end of the QT interval. The implications of these findings for the understanding of VFT measurements are discussed.

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Year:  1975        PMID: 1201569     DOI: 10.1093/cvr/9.5.613

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN: 0008-6363            Impact factor:   10.787


  11 in total

1.  Effects of calcium channel agonism by Bay-K-8644 on ventricular fibrillation threshold of isolated heart.

Authors:  M G Worthington; L H Opie
Journal:  Cardiovasc Drugs Ther       Date:  1992-12       Impact factor: 3.727

2.  The role of cyclic adenosine monophosphate in adrenergic effects on ventricular vulnerability to fibrillation in the isolated perfused rat heart.

Authors:  W F Lubbe; T Podzuweit; P S Daries; L H Opie
Journal:  J Clin Invest       Date:  1978-05       Impact factor: 14.808

3.  Changes in the incidence and duration of ventricular fibrillation in dependence on the extraneuronal accumulation of isoprenaline in the perfused rat heart.

Authors:  K Sono; K Kurahashi; M Fujiwara
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-10       Impact factor: 3.000

4.  Blood cardioplegia delivery. Deleterious effects of potassium versus lidocaine.

Authors:  F G Leicher; P Magrassi; P J LaRaia; W M Derkac; M J Buckley; W G Austen
Journal:  Ann Surg       Date:  1983-09       Impact factor: 12.969

5.  Development of a severe model of early coronary artery ligation-induced dysrhythmias in the anaesthetized rat.

Authors:  R J Marshall; A W Muir; E Winslow
Journal:  Br J Pharmacol       Date:  1981-08       Impact factor: 8.739

6.  The effect of calcium concentration on spontaneous ventricular defibrillation and VF threshold.

Authors:  M Arad; Y Mahler; S Rogel; G Uretzky
Journal:  Basic Res Cardiol       Date:  1987 Jul-Aug       Impact factor: 17.165

7.  Chronophysiological view on changes of the electrical stability of the heart and heart rate under pentobarbital sodium and ketamine/xylazine anesthesia in a hypoventilation-reoxygenation rat model.

Authors:  Pavol Svorc; Roman Benacka; Imola Bracoková; Stefan Kujaník
Journal:  Exp Clin Cardiol       Date:  2004

8.  The effect of hypoxic myocardial preconditioning is highly dependent on the light-dark cycle in Wistar rats.

Authors:  Pavol Svorc; Roman Benacka
Journal:  Exp Clin Cardiol       Date:  2008

9.  The effect of heart rate on the termination of electrically induced ventricular fibrillation in the isolated perfused rat heart.

Authors:  M Arad; S Rogel; Y Mahler; G Uretzky
Journal:  Basic Res Cardiol       Date:  1988 Nov-Dec       Impact factor: 17.165

10.  Carbachol and dibutyryl cyclic GMP on the vulnerability to ventricular fibrillation in rat isolated hearts.

Authors:  A Daugherty; B Woodward
Journal:  Br J Pharmacol       Date:  1985-07       Impact factor: 8.739

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