Literature DB >> 12015143

Will the real integrin please stand up?

Robert C Liddington1.   

Abstract

Recent structure-function studies of integrins are beginning to unravel the mechanism of signal transduction across the plasma membrane, but controversy exists over the nature of the conformational changes underlying this process.

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Year:  2002        PMID： 12015143     DOI： 10.1016/s0969-2126(02)00766-9

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  5 in total

Review 1.  Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.

Authors:  Charles A Whittaker; Richard O Hynes
Journal:  Mol Biol Cell       Date:  2002-10       Impact factor: 4.138

2.  Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography.

Authors:  Brian D Adair; Mark Yeager
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-18       Impact factor: 11.205

3.  Novel activating and inactivating mutations in the integrin beta1 subunit A domain.

Authors:  Stephanie J Barton; Mark A Travis; Janet A Askari; Patrick A Buckley; Susan E Craig; Martin J Humphries; A Paul Mould
Journal:  Biochem J       Date:  2004-06-01       Impact factor: 3.857

4.  Integrin alphaIIbbeta3:ligand interactions are linked to binding-site remodeling.

Authors:  Roy R Hantgan; Mary C Stahle; John H Connor; David A Horita; Mattia Rocco; Mary A McLane; Sergiy Yakovlev; Leonid Medved
Journal:  Protein Sci       Date:  2006-08       Impact factor: 6.725

5.  How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation.

Authors:  Eileen Puklin-Faucher; Mu Gao; Klaus Schulten; Viola Vogel
Journal:  J Cell Biol       Date:  2006-10-23       Impact factor: 10.539
  5 in total

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