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Literature DB >> 12010869

Primary biliary cirrhosis: seeking the silent partner of autoimmunity.

Abstract

Primary biliary cirrhosis is a disorder characterised by an intense inflammatory response in the septal and interlobular bile ducts and is considered to be an autoimmune disease. Evidence to suggest that chronic viral infection could be a crucial element in the development of biliary epithelial cell damage and activation of the associated autoimmune response is reviewed

Entities: Disease

Mesh：

Substances：

Year: 2002 PMID： 12010869 PMCID： PMC1773250 DOI： 10.1136/gut.50.6.743

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

30 in total

1. Autoimmune diseases: genes, bugs and failed regulation.

Authors: J Ermann; C G Fathman
Journal: Nat Immunol Date: 2001-09 Impact factor: 25.606

Review 2. Drug-induced cholestasis.

Authors: S Chitturi; G C Farrell
Journal: Semin Gastrointest Dis Date: 2001-04

3. Natural history of early primary biliary cirrhosis.

Authors: J V Metcalf; H C Mitchison; J M Palmer; D E Jones; M F Bassendine; O F James
Journal: Lancet Date: 1996-11-23 Impact factor: 79.321

Review 4. PBC and AMA--what is the connection?

Authors: J Neuberger; R Thomson
Journal: Hepatology Date: 1999-01 Impact factor: 17.425

5. Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

Authors: L Klein; M Klugmann; K A Nave; V K Tuohy; B Kyewski
Journal: Nat Med Date: 2000-01 Impact factor: 53.440

6. Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis: applications of a semiautomated assay.

Authors: K L Teoh; M J Rowley; H Zafirakis; E R Dickson; R H Wiesner; M E Gershwin; I R MacKay
Journal: Hepatology Date: 1994-11 Impact factor: 17.425

7. Primary biliary cirrhosis. High proportions of B cells in blood and liver tissue produce anti-mitochondrial antibodies of several Ig classes.

Authors: A Björkland; L Lööf; I Mendel-Hartvig; T H Tötterman
Journal: J Immunol Date: 1994-09-15 Impact factor: 5.422

8. Heterogeneity of combinatorial human autoantibodies against PDC-E2 and biliary epithelial cells in patients with primary biliary cirrhosis.

Authors: S Cha; P S Leung; R L Coppel; J Van de Water; A A Ansari; M E Gershwin
Journal: Hepatology Date: 1994-09 Impact factor: 17.425

9. Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides.

Authors: T Tsuchida; K C Parker; R V Turner; H F McFarland; J E Coligan; W E Biddison
Journal: Proc Natl Acad Sci U S A Date: 1994-11-08 Impact factor: 11.205

10. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire.

Authors: A C Anderson; L B Nicholson; K L Legge; V Turchin; H Zaghouani; V K Kuchroo
Journal: J Exp Med Date: 2000-03-06 Impact factor: 14.307

5 in total

Primary biliary cirrhosis: seeking the silent partner of autoimmunity.

1. Autoimmune diseases: genes, bugs and failed regulation.

Review 2. Drug-induced cholestasis.

3. Natural history of early primary biliary cirrhosis.

Review 4. PBC and AMA--what is the connection?

5. Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

6. Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis: applications of a semiautomated assay.

7. Primary biliary cirrhosis. High proportions of B cells in blood and liver tissue produce anti-mitochondrial antibodies of several Ig classes.

8. Heterogeneity of combinatorial human autoantibodies against PDC-E2 and biliary epithelial cells in patients with primary biliary cirrhosis.

9. Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides.

10. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire.

Review 1. Primary biliary cirrhosis: From bench to bedside.

Review 2. Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis.

Review 3. Primary biliary cirrhosis: what do autoantibodies tell us?

Review 4. Pathogenesis of primary biliary cirrhosis: a unifying model.

Review 5. Concept on the pathogenesis and treatment of primary biliary cirrhosis.