Literature DB >> 12009925

Low-density lipoprotein reconstituted by pyropheophorbide cholesteryl oleate as target-specific photosensitizer.

Gang Zheng1, Hui Li, Min Zhang, Sissel Lund-Katz, Britton Chance, Jerry D Glickson.   

Abstract

To target tumors overexpressing low-density lipoprotein receptors (LDLr), a pyropheophorbide cholesterol oleate conjugate was synthesized and successfully reconstituted into the low-density lipoprotein (LDL) lipid core. Laser scanning confocal microscopy studies demonstrated that this photosensitizer-reconstituted LDL can be internalized via LDLr by human hepatoblastoma G(2) (HepG(2)) tumor cells.

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Year:  2002        PMID： 12009925     DOI： 10.1021/bc025516h

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  17 in total

1.  Magnetic resonance imaging detection of tumor cells by targeting low-density lipoprotein receptors with Gd-loaded low-density lipoprotein particles.

Authors:  Simonetta Geninatti Crich; Stefania Lanzardo; Diego Alberti; Simona Belfiore; Anna Ciampa; Giovanni B Giovenzana; Clara Lovazzano; Roberto Pagliarin; Silvio Aime
Journal:  Neoplasia       Date:  2007-12       Impact factor: 5.715

2.  Gold nanocrystal labeling allows low-density lipoprotein imaging from the subcellular to macroscopic level.

Authors:  Iris E Allijn; Wei Leong; Jun Tang; Anita Gianella; Aneta J Mieszawska; Francois Fay; Ge Ma; Stewart Russell; Catherine B Callo; Ronald E Gordon; Emine Korkmaz; Jan Andries Post; Yiming Zhao; Hans C Gerritsen; Axel Thran; Roland Proksa; Heiner Daerr; Gert Storm; Valentin Fuster; Edward A Fisher; Zahi A Fayad; Willem J M Mulder; David P Cormode
Journal:  ACS Nano       Date:  2013-10-17       Impact factor: 15.881

3.  Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents.

Authors:  Gang Zheng; Juan Chen; Hui Li; Jerry D Glickson
Journal:  Proc Natl Acad Sci U S A       Date:  2005-11-23       Impact factor: 11.205

4.  Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents.

Authors:  Nadia Anikeeva; Yuri Sykulev; Edward J Delikatny; Anatoliy V Popov
Journal:  Am J Nucl Med Mol Imaging       Date:  2014-09-06

5.  In vivo detection of phospholipase C by enzyme-activated near-infrared probes.

Authors:  Theresa M Mawn; Anatoliy V Popov; Nancy J Beardsley; Klara Stefflova; Matthew Milkevitch; Gang Zheng; E James Delikatny
Journal:  Bioconjug Chem       Date:  2011-11-29       Impact factor: 4.774

6.  Tuning Pharmacokinetics to Improve Tumor Accumulation of a Prostate-Specific Membrane Antigen-Targeted Phototheranostic Agent.

Authors:  Kara M Harmatys; Marta Overchuk; Juan Chen; Lili Ding; Ying Chen; Martin G Pomper; Gang Zheng
Journal:  Bioconjug Chem       Date:  2018-10-29       Impact factor: 4.774

Review 7.  Lipoproteins and lipoprotein mimetics for imaging and drug delivery.

Authors:  C Shad Thaxton; Jonathan S Rink; Pratap C Naha; David P Cormode
Journal:  Adv Drug Deliv Rev       Date:  2016-04-29       Impact factor: 15.470

8.  Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers.

Authors:  Pui-Chi Lo; Juan Chen; Klara Stefflova; Michael S Warren; Roya Navab; Bizhan Bandarchi; Stefanie Mullins; Ming Tsao; Jonathan D Cheng; Gang Zheng
Journal:  J Med Chem       Date:  2009-01-22       Impact factor: 7.446

9.  Nanocrystal Core Lipoprotein Biomimetics for Imaging of Lipoproteins and Associated Diseases.

Authors:  Francois Fay; Brenda L Sanchez-Gaytan; David P Cormode; Torjus Skajaa; Edward A Fisher; Zahi A Fayad; Willem J M Mulder
Journal:  Curr Cardiovasc Imaging Rep       Date:  2013-02-01

10.  One minute, sub-one-watt photothermal tumor ablation using porphysomes, intrinsic multifunctional nanovesicles.

Authors:  Cheng S Jin; Jonathan F Lovell; Gang Zheng
Journal:  J Vis Exp       Date:  2013-09-17       Impact factor: 1.355
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