| Literature DB >> 12009565 |
Abstract
Cytokines produced by innate immune response can profoundly influence the subsequent adaptive immunity. IL-15 and -18 are two of several mediators produced by macrophages that perform such a function. Here we present recent data mainly from our own laboratory illustrating the important role of IL-15 and -18 in the induction and perpetuation of chronic inflammation during experimental and clinical rheumatoid synovitis.Entities:
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Year: 2002 PMID: 12009565 DOI: 10.1016/s0161-5890(02)00014-7
Source DB: PubMed Journal: Mol Immunol ISSN: 0161-5890 Impact factor: 4.407