Literature DB >> 12007993

The role of the transferrin-transferrin-receptor system in drug delivery and targeting.

Hongyan Li1, Hongzhe Sun, Zhong Ming Qian.   

Abstract

Exploration of the potential of site-specific and target-oriented drug delivery systems has gained interest recently. Indeed, the efficient cellular mechanism of transferrin uptake has been exploited for the delivery not only of anticancer drugs and proteins, but also of therapeutic genes into proliferating malignant cells that overexpress transferrin receptors. In particular, the transferrin receptor offers great promise in the delivery of therapeutic agents across the blood-brain barrier to the brain.

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Year:  2002        PMID： 12007993     DOI： 10.1016/s0165-6147(02)01989-2

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  24 in total

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3.  Surface-functionalized nanoparticles for targeted gene delivery across nasal respiratory epithelium.

Authors:  Sneha Sundaram; Shyamal K Roy; Balamurali K Ambati; Uday B Kompella
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4.  Evaluation of Nonferrous Metals as Potential In Vivo Tracers of Transferrin-Based Therapeutics.

Authors:  Hanwei Zhao; Shunhai Wang; Son N Nguyen; S Gokhan Elci; Igor A Kaltashov
Journal:  J Am Soc Mass Spectrom       Date:  2015-09-21       Impact factor: 3.109

5.  Entry modes of ellipsoidal nanoparticles on a membrane during clathrin-mediated endocytosis.

Authors:  Hua Deng; Prashanta Dutta; Jin Liu
Journal:  Soft Matter       Date:  2019-06-26       Impact factor: 3.679

6.  Membrane-inserted conformation of transmembrane domain 4 of divalent-metal transporter.

Authors:  Hongyan Li; Fei Li; Hongzhe Sun; Zhong Ming Qian
Journal:  Biochem J       Date:  2003-06-15       Impact factor: 3.857

7.  Uptake of diterbium transferrin, a potential multi-photon-excited microscopy probe, into human leukemia K562 cells via a transferrin-receptor-mediated process.

Authors:  Lan Yuan; Ping Du; Kui Wang; Xiao-Gai Yang
Journal:  J Biol Inorg Chem       Date:  2009-07-15       Impact factor: 3.358

8.  Mass spectrometry-guided optimization and characterization of a biologically active transferrin-lysozyme model drug conjugate.

Authors:  Son N Nguyen; Cedric E Bobst; Igor A Kaltashov
Journal:  Mol Pharm       Date:  2013-04-10       Impact factor: 4.939

9.  Receptor recognition of transferrin bound to lanthanides and actinides: a discriminating step in cellular acquisition of f-block metals.

Authors:  Gauthier J-P Deblonde; Manuel Sturzbecher-Hoehne; Anne B Mason; Rebecca J Abergel
Journal:  Metallomics       Date:  2013-06       Impact factor: 4.526

10.  An efficient targeted drug delivery through apotransferrin loaded nanoparticles.

Authors:  Athuluri Divakar Sai Krishna; Raj Kumar Mandraju; Golla Kishore; Anand Kumar Kondapi
Journal:  PLoS One       Date:  2009-10-02       Impact factor: 3.240
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