Literature DB >> 12007706

In vitro antiplasmodial activity of extracts of Argentinian plants.

S Debenedetti1, L Muschietti, C van Baren, M Clavin, A Broussalis, V Martino, P J Houghton, D Warhurst, J Steele.   

Abstract

Fifteen extracts from nine selected Argentine medicinal plants were tested for their antiplasmodial activity in vitro by assessing their ability to inhibit the uptake of [3H]-hypoxanthine into the Plasmodium falciparum K1 pyrimethamine/chloroquine resistant strain. The methanol extract of Satureja parvifolia showed good antiplasmodial activity (IC(50) 3 microg/ml). Inhibition of the growth of P. falciparum was also observed with aqueous extracts of Buddleja globosa and S. parvifolia.

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Year:  2002        PMID: 12007706     DOI: 10.1016/s0378-8741(02)00024-7

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  4 in total

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Review 4.  Malaria in South America: a drug discovery perspective.

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  4 in total

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