Literature DB >> 12007537

ACRP30, a new hormone controlling fat and glucose metabolism.

Tsu-Shuen Tsao1, Harvey F Lodish, Joachim Fruebis.   

Abstract

Adipocyte complement-related protein of 30 kDa (ACRP30) is a secreted serum protein expressed exclusively in differentiated adipocytes. Recent studies have indicated that its expression and serum levels are reduced in humans and animals with obesity and insulin resistance. Metabolic studies have demonstrated a role for ACRP30 in the regulation of glucose and lipid homeostasis. This review will describe the current literature on the biochemistry of ACRP30 and its physiological functions. We will also discuss issues that are relevant to the directions of future research.

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Year:  2002        PMID: 12007537     DOI: 10.1016/s0014-2999(02)01430-9

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  53 in total

1.  Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation.

Authors:  Eva Tomas; Tsu-Shuen Tsao; Asish K Saha; Heather E Murrey; Cheng cheng Zhang Cc; Samar I Itani; Harvey F Lodish; Neil B Ruderman
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-27       Impact factor: 11.205

2.  Adiponectin receptors are downregulated in human gastric cancer.

Authors:  Kensuke Otani; Joji Kitayama; Takao Kamei; Daisuke Soma; Hideyo Miyato; Toshimasa Yamauchi; Takashi Kadowaki; Hirokazu Nagawa
Journal:  J Gastroenterol       Date:  2010-03-25       Impact factor: 7.527

3.  Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells.

Authors:  R B Ceddia; R Somwar; A Maida; X Fang; G Bikopoulos; G Sweeney
Journal:  Diabetologia       Date:  2004-12-24       Impact factor: 10.122

Review 4.  Assembly of adiponectin oligomers.

Authors:  Tsu-Shuen Tsao
Journal:  Rev Endocr Metab Disord       Date:  2014-06       Impact factor: 6.514

5.  Adiponectin deficiency: a model of pulmonary hypertension associated with pulmonary vascular disease.

Authors:  Ross Summer; Christopher A Fiack; Yasumasa Ikeda; Kaori Sato; Daniel Dwyer; Noriyuki Ouchi; Alan Fine; Harrison W Farber; Kenneth Walsh
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2009-06-26       Impact factor: 5.464

6.  Increased oxidative stress in obesity and its impact on metabolic syndrome.

Authors:  Shigetada Furukawa; Takuya Fujita; Michio Shimabukuro; Masanori Iwaki; Yukio Yamada; Yoshimitsu Nakajima; Osamu Nakayama; Makoto Makishima; Morihiro Matsuda; Iichiro Shimomura
Journal:  J Clin Invest       Date:  2004-12       Impact factor: 14.808

7.  Acetyl-L-Carnitine Ameliorates Metabolic and Endocrine Alterations in Women with PCOS: A Double-Blind Randomized Clinical Trial.

Authors:  Saman Tauqir; Momina Israr; Bushra Rauf; Muhammad Omar Malik; Syed Hamid Habib; Fawad Ali Shah; Muhammad Usman; Muhammad Asif Raza; Inayat Shah; Haroon Badshah; Ehtesham Ehtesham; Mohsin Shah
Journal:  Adv Ther       Date:  2021-05-28       Impact factor: 3.845

8.  Nitric oxide bioavailability and adiponectin production in chronic systolic heart failure: relation to severity of cardiac dysfunction.

Authors:  W H Wilson Tang; Kevin Shrestha; Wilson Tong; Zeneng Wang; Richard W Troughton; Allen G Borowski; Allan L Klein; Stanley L Hazen
Journal:  Transl Res       Date:  2013-03-13       Impact factor: 7.012

9.  Globular adiponectin upregulates nitric oxide production in vascular endothelial cells.

Authors:  Y Hattori; M Suzuki; S Hattori; K Kasai
Journal:  Diabetologia       Date:  2003-10-09       Impact factor: 10.122

10.  Disulfide-dependent self-assembly of adiponectin octadecamers from trimers and presence of stable octadecameric adiponectin lacking disulfide bonds in vitro.

Authors:  David B Briggs; Christopher M Jones; Ellene H Mashalidis; Martha Nuñez; Andrew C Hausrath; Vicki H Wysocki; Tsu-Shuen Tsao
Journal:  Biochemistry       Date:  2009-12-29       Impact factor: 3.162

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