Literature DB >> 12005427

Apoptosome: the cellular engine for the activation of caspase-9.

Yigong Shi1.   

Abstract

Characterization of the apoptosome by cryo-EM reveals a wheel-shaped heptameric assembly involving Apaf-1 and cytochrome c. This structure provides a framework for understanding the activation mechanisms of caspase-9, an important initiator caspase in apoptosis.

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Year:  2002        PMID： 12005427     DOI： 10.1016/s0969-2126(02)00732-3

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  38 in total

Review 1.  Applications of molecular imaging.

Authors:  Craig J Galbán; Stefanie Galbán; Marcian E Van Dort; Gary D Luker; Mahaveer S Bhojani; Alnawaz Rehemtulla; Brian D Ross
Journal:  Prog Mol Biol Transl Sci       Date:  2010       Impact factor: 3.622

2.  Mechanism of caspase-9 activation during hypoxia in the cerebral cortex of newborn piglets: the role of Src kinase.

Authors:  Maria Delivoria-Papadopoulos
Journal:  Neurosci Lett       Date:  2012-06-21       Impact factor: 3.046

3.  Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila.

Authors:  Alaeddin Abu-Zant; Marina Santic; Maelle Molmeret; Snake Jones; Jürgen Helbig; Yousef Abu Kwaik
Journal:  Infect Immun       Date:  2005-09       Impact factor: 3.441

Review 4.  Death receptor signals to mitochondria.

Authors:  Roya Khosravi-Far; Mauro Degli Esposti
Journal:  Cancer Biol Ther       Date:  2004-11-18       Impact factor: 4.742

5.  The emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis.

Authors:  Ricardo D Moreno; Paulina Urriola-Muñoz; Raúl Lagos-Cabré
Journal:  Spermatogenesis       Date:  2011-07-01

Review 6.  The PYRIN domain in signal transduction.

Authors:  Christian Stehlik
Journal:  Curr Protein Pept Sci       Date:  2007-06       Impact factor: 3.272

7.  A transgenic mouse for imaging caspase-dependent apoptosis within the skin.

Authors:  Divya Khanna; Christin A Hamilton; Mahaveer S Bhojani; Kuei C Lee; Andrej Dlugosz; Brian D Ross; Alnawaz Rehemtulla
Journal:  J Invest Dermatol       Date:  2010-04-01       Impact factor: 8.551

Review 8.  Metabolic Regulation of Apoptosis in Cancer.

Authors:  K Matsuura; K Canfield; W Feng; M Kurokawa
Journal:  Int Rev Cell Mol Biol       Date:  2016-07-30       Impact factor: 6.813

9.  Modulation of Diabetes-Induced Oxidative Stress, Apoptosis, and Ca2+ Entry Through TRPM2 and TRPV1 Channels in Dorsal Root Ganglion and Hippocampus of Diabetic Rats by Melatonin and Selenium.

Authors:  Mehmet Cemal Kahya; Mustafa Nazıroğlu; İshak Suat Övey
Journal:  Mol Neurobiol       Date:  2016-03-09       Impact factor: 5.590

10.  Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells.

Authors:  Olivier E Pardo; Adeline Lesay; Alexandre Arcaro; Rita Lopes; Bee Ling Ng; Patricia H Warne; Iain A McNeish; Teresa D Tetley; Nicholas R Lemoine; Huseyin Mehmet; Michael J Seckl; Julian Downward
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272
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