Literature DB >> 1200526

Deficiency of the second component of complement (C2) with chronic vasculitis.

P Friend, J E Repine, C C Clawson, A F Michael.   

Abstract

A patient had complete deficiency of the second component of complement associated with chronic vasculitis and increased susceptibility to infection. We discuss here results of the complement profile, histocompatibility typing, and studies of the functional properties of patient plasma or serum in chemotaxis and opsonization in relation to the disease entity and host susceptibility to infection.

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Year:  1975        PMID: 1200526     DOI: 10.7326/0003-4819-83-6-813

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN: 0003-4819            Impact factor:   25.391


  8 in total

1.  Vasculitis with probable familial C2 deficiency. (Case 1). Systemic lupus erythematosus with familial C2 deficiency. (Case 2).

Authors:  J R Rendall
Journal:  Proc R Soc Med       Date:  1977-10

2.  The location of C2, C4, and BF relative to HLA-B and HLA-D.

Authors:  D D Raum; Z L Awdeh; D Glass; E Yunis; C A Alper
Journal:  Immunogenetics       Date:  1981-03-01       Impact factor: 2.846

3.  Influence of a deficiency of the second component of complement on the bactericidal activity of neutrophils in vitro.

Authors:  J E Repine; C C Clawson; P S Friend
Journal:  J Clin Invest       Date:  1977-05       Impact factor: 14.808

4.  Inherited deficiency of the second component of complement. Rheumatic disease associations.

Authors:  D Glass; D Raum; D Gibson; J S Stillman; P H Schur
Journal:  J Clin Invest       Date:  1976-10       Impact factor: 14.808

5.  Hereditary C2 deficiency and systemic lupus erythematosus associated with severe glomerulonephritis.

Authors:  J L Roberts; M M Schwartz; E J Lewis
Journal:  Clin Exp Immunol       Date:  1978-02       Impact factor: 4.330

6.  Recurrent pyogenic infections in individuals with absence of the second component of complement.

Authors:  H A Sampson; A M Walchner; P J Baker
Journal:  J Clin Immunol       Date:  1982-01       Impact factor: 8.317

7.  Defective activation of the alternative pathway of complement in patients with homozygous C2 deficiency: studies in two unrelated families.

Authors:  R Schwertz; E Esser; R A Seger; A Rubinstein; G Hauptmann; V Wahn
Journal:  Eur J Pediatr       Date:  1991-07       Impact factor: 3.183

8.  Association of low C2 and C4 serum levels with the HLA-DW2 allele in healthy individuals.

Authors:  C Nerl; H Grosse-Wilde; G Valet
Journal:  J Exp Med       Date:  1978-09-01       Impact factor: 14.307

  8 in total

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