OBJECTIVE: To assess the effect on the haemoglobin concentrations of schoolchildren of weekly iron tablets administered by teachers. DESIGN:Sixty schools were randomly assigned to two groups: in 30 schools children were given weekly for 10 weeks a tablet providing 65 mg of iron and 0.25 mg of folic acid; in the other 30 schools no iron tablets were given. All children were dewormed and given vitamin A before the study began. The haemoglobin concentration of up to 20 randomly selected children in each school was estimated before and 2 weeks after the end of treatment. SETTING:Rural community schools in Kolondieba district of Mali. SUBJECTS: Some 1113 schoolchildren aged 6-19 years with a mean of 11.4 years. RESULTS: The haemoglobin concentration of treated children rose on average by 1.8 g l(-1) and the prevalence of anaemia fell by 8.2%; in untreated children the haemoglobin concentration fell by an average of -2.7 g l(-1) and the prevalence of anaemia rose by 9.4%. The fall in haemoglobin concentration among untreated girls of -4.0 g l(-1) was greater than in untreated boys (-0.3 g l(-1) ). CONCLUSIONS: Weekly iron tablets given by teachers prevented a general fall in the haemoglobin concentrations of untreated children, and led to a small but statistically significant rise among treated children. Young children benefited more than children aged >or=12 years, and girls benefited more than boys.
RCT Entities:
OBJECTIVE: To assess the effect on the haemoglobin concentrations of schoolchildren of weekly iron tablets administered by teachers. DESIGN: Sixty schools were randomly assigned to two groups: in 30 schools children were given weekly for 10 weeks a tablet providing 65 mg of iron and 0.25 mg of folic acid; in the other 30 schools no iron tablets were given. All children were dewormed and given vitamin A before the study began. The haemoglobin concentration of up to 20 randomly selected children in each school was estimated before and 2 weeks after the end of treatment. SETTING: Rural community schools in Kolondieba district of Mali. SUBJECTS: Some 1113 schoolchildren aged 6-19 years with a mean of 11.4 years. RESULTS: The haemoglobin concentration of treated children rose on average by 1.8 g l(-1) and the prevalence of anaemia fell by 8.2%; in untreated children the haemoglobin concentration fell by an average of -2.7 g l(-1) and the prevalence of anaemia rose by 9.4%. The fall in haemoglobin concentration among untreated girls of -4.0 g l(-1) was greater than in untreated boys (-0.3 g l(-1) ). CONCLUSIONS: Weekly iron tablets given by teachers prevented a general fall in the haemoglobin concentrations of untreated children, and led to a small but statistically significant rise among treated children. Young children benefited more than children aged >or=12 years, and girls benefited more than boys.
Authors: Siân E Clarke; Matthew C H Jukes; J Kiambo Njagi; Lincoln Khasakhala; Bonnie Cundill; Julius Otido; Christopher Crudder; Benson B A Estambale; Simon Brooker Journal: Lancet Date: 2008-07-12 Impact factor: 79.321