Literature DB >> 12001340

Self-mutilation in rabbits following intramuscular ketamine-xylazine-acepromazine injections.

P Vachon1.   

Abstract

Following hind leg intramuscular injections of ketamine, xylazine, and acepromazine, 4 of 6 rabbits exhibited self-mutilation of the digits. At necropsy, the affected sciatic nerve appeared enlarged. Lymphohistiocytic perineural inflammation and fibrosis were observed, together with nerve degeneration. Neuronal regeneration as the reason for self-mutilation is discussed.

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Year:  1999        PMID： 12001340      PMCID： PMC1539777     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  7 in total

1.  Axonal degeneration and self-mutilation as a complication of the intramuscular use of ketamine and xylazine in rabbits.

Authors:  T M Beyers; J A Richardson; M D Prince
Journal:  Lab Anim Sci       Date:  1991-10

2.  Diet can modify autotomy behavior in rats following peripheral neurectomy.

Authors:  Y Shir; A Ratner; Z Seltzer
Journal:  Neurosci Lett       Date:  1997-10-31       Impact factor: 3.046

Review 3.  Deafferentation and chronic pain in animals: an evaluation of evidence suggesting autotomy is related to pain.

Authors:  Terence J Coderre; Robert W Grimes; Ronald Melzack
Journal:  Pain       Date:  1986-07       Impact factor: 6.961

4.  Tissue response to intramuscular and intraperitoneal injections of ketamine and xylazine in rats.

Authors:  K L Smiler; S Stein; K L Hrapkiewicz; J R Hiben
Journal:  Lab Anim Sci       Date:  1990-01

5.  Local myotoxicity of ketamine hydrochloride in the marmoset.

Authors:  C W Davy; P N Trennery; J G Edmunds; J F Altman; D A Eichler
Journal:  Lab Anim       Date:  1987-01       Impact factor: 2.471

6.  Peripheral nerve pathology following sciatic cryoneurolysis: relationship to neuropathic behaviors in the rat.

Authors:  R Wagner; J A DeLeo; H M Heckman; R R Myers
Journal:  Exp Neurol       Date:  1995-06       Impact factor: 5.330

7.  Muscle necrosis in Syrian hamsters resulting from intramuscular injections of ketamine and xylazine.

Authors:  D J Gaertner; K R Boschert; T R Schoeb
Journal:  Lab Anim Sci       Date:  1987-02
  7 in total
  5 in total

1.  Administration of substances to laboratory animals: routes of administration and factors to consider.

Authors:  Patricia V Turner; Thea Brabb; Cynthia Pekow; Mary Ann Vasbinder
Journal:  J Am Assoc Lab Anim Sci       Date:  2011-09       Impact factor: 1.232

2.  A Rabbit Model for Peripheral Nerve Reconstruction Studies Avoiding Automutilation Behavior.

Authors:  Jonathan A Sorkin; Ziv Rechany; Mara Almog; Nina Dietzmeyer; Yuval Shapira; Kirsten Haastert-Talini; Shimon Rochkind
Journal:  J Brachial Plex Peripher Nerve Inj       Date:  2022-06-21

3.  Beyond-use dating of extemporaneously compounded ketamine, acepromazine, and xylazine: safety, stability, and efficacy over time.

Authors:  Brett J Taylor; Steven A Orr; Jennifer L Chapman; Diana E Fisher
Journal:  J Am Assoc Lab Anim Sci       Date:  2009-11       Impact factor: 1.232

4.  Impact of repeated anesthesia with ketamine and xylazine on the well-being of C57BL/6JRj mice.

Authors:  Katharina Hohlbaum; Bettina Bert; Silke Dietze; Rupert Palme; Heidrun Fink; Christa Thöne-Reineke
Journal:  PLoS One       Date:  2018-09-19       Impact factor: 3.240

5.  A sciatic nerve gap-injury model in the rabbit.

Authors:  Antonio Merolli; Michelle Li; Gregory Voronin; Lauren Bright
Journal:  J Mater Sci Mater Med       Date:  2022-01-21       Impact factor: 3.896
  5 in total

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