| Literature DB >> 12000564 |
L Sherman1, J Y Ye, O Albert, T B Norris.
Abstract
We demonstrate adaptive aberration correction for depth-induced spherical aberration in a multiphoton scanning microscope with a micromachined deformable mirror. Correction was made using a genetic learning algorithm with two-photon fluorescence intensity feedback to determine the desired shape for an adaptive mirror. For a 40x/0.6 NA long working distance objective, the axial scanning range was increased from 150 mm to 600 mm.Mesh:
Substances:
Year: 2002 PMID: 12000564 DOI: 10.1046/j.1365-2818.2002.01004.x
Source DB: PubMed Journal: J Microsc ISSN: 0022-2720 Impact factor: 1.758