| Literature DB >> 12000306 |
David W Hoard1, Eric D Moher, Michael J Martinelli, Bryan H Norman.
Abstract
[reaction: see text] A synthesis of cryptophycin 52 is reported using a Shi epoxidation strategy to install the epoxide moiety in a diastereoselective fashion. Several epoxidation results for cryptophycin substrates are disclosed followed by a discussion of the details relating to the preparation of cryptophycin 52 in two synthetic steps from one of the intermediate epoxides.Entities:
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Year: 2002 PMID： 12000306 DOI： 10.1021/ol025933+
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005