Literature DB >> 12000282

Synthesis of D-erythro-dihydrosphingosine and D-xylo-phytosphingosine from a serine-derived 1,5-dioxaspiro[3.2]hexane template.

Albert J Ndakala1, Mehrnoosh Hashemzadeh, Regina C So, Amy R Howell.   

Abstract

[reaction: see text] A serine-derived 1,5-dioxaspiro[3.2]hexane template is shown to be a useful precursor for both aminodiol and aminotriol sphingoid bases by its conversion to D-erythro-dihydrosphingosine and D-xylo-phytoshingosine.

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Year:  2002        PMID： 12000282     DOI： 10.1021/ol0200448

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Synthesis of Unusually Strained Spiro Ring Systems and Their Exploits in Synthesis.

Authors:  Richard J Duffy; Kay A Morris; Daniel Romo
Journal:  Tetrahedron       Date:  2009-09-01       Impact factor: 2.457

2.  Preparation of anti-vicinal amino alcohols: asymmetric synthesis of D-erythro-sphinganine, (+)-spisulosine, and D-ribo-phytosphingosine.

Authors:  Ewen D D Calder; Ahmed M Zaed; Andrew Sutherland
Journal:  J Org Chem       Date:  2013-07-03       Impact factor: 4.354
  2 in total

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