Literature DB >> 12000261

Stereospecific synthesis of cryptophycin 1.

Lian-Hai Li1, Marcus A Tius.   

Abstract

[reaction: see text] A brief stereospecific synthesis of cryptophycin 1 is described in which (R)-mandelic acid serves as the sole source of asymmetry for unit A. The key step is a hetero-Diels-Alder cycloaddition.

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Year:  2002        PMID： 12000261     DOI： 10.1021/ol020001r

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Thionium ion initiated medium-sized ring formation: the total synthesis of asteriscunolide D.

Authors:  Barry M Trost; Aaron C Burns; Mark J Bartlett; Thomas Tautz; Andrew H Weiss
Journal:  J Am Chem Soc       Date:  2012-01-10       Impact factor: 15.419

2.  Asymmetric Syntheses of Potent Antitumor Macrolides Cryptophycin B and Arenastatin A.

Authors:  Arun K Ghosh; A Bischoff
Journal:  European J Org Chem       Date:  2004-04-27

3.  Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide-herboxidiene hybrid analog and related derivatives.

Authors:  Chandraiah Lagisetti; Maria V Yermolina; Lalit Kumar Sharma; Gustavo Palacios; Brett J Prigaro; Thomas R Webb
Journal:  ACS Chem Biol       Date:  2013-12-30       Impact factor: 5.100
  3 in total

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