Literature DB >> 11997029

The presence of 4-hydroxyphenylacetic acid in human saliva and the possibility of its nitration by salivary nitrite in the stomach.

Umeo Takahama1, Takayuki Oniki, Hideaki Murata.   

Abstract

Human saliva contained 4-hydroxyphenylacetic acid (HPA) (2-10 microM) and nitrite (60-300 microM). HPA was nitrated to 4-hydroxy-3-nitrophenylacetic acid (NO2HPA) when HPA and sodium nitrite were mixed at pH 1.0. NO2HPA was also formed when saliva was incubated under acidic conditions. These results suggest that salivary HPA is nitrated to NO2HPA when saliva is swallowed into the stomach.

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Year:  2002        PMID： 11997029     DOI： 10.1016/s0014-5793(02)02659-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

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Journal:  J Biol Chem       Date:  2014-05-15       Impact factor: 5.157

2.  Simultaneous measurement and quantitation of 4-hydroxyphenylacetic acid and dopamine with fast-scan cyclic voltammetry.

Authors:  Mimi Shin; Sam V Kaplan; Kayla D Raider; Michael A Johnson
Journal:  Analyst       Date:  2015-03-18       Impact factor: 4.616

3.  Transcriptional regulation of the nadA gene in Neisseria meningitidis impacts the prediction of coverage of a multicomponent meningococcal serogroup B vaccine.

Authors:  Luca Fagnocchi; Alessia Biolchi; Francesca Ferlicca; Giuseppe Boccadifuoco; Brunella Brunelli; Sébastien Brier; Nathalie Norais; Emiliano Chiarot; Giuliano Bensi; J Simon Kroll; Mariagrazia Pizza; John Donnelly; Marzia Monica Giuliani; Isabel Delany
Journal:  Infect Immun       Date:  2012-12-10       Impact factor: 3.441

4.  In the NadR regulon, adhesins and diverse meningococcal functions are regulated in response to signals in human saliva.

Authors:  Luca Fagnocchi; Eva Pigozzi; Vincenzo Scarlato; Isabel Delany
Journal:  J Bacteriol       Date:  2011-11-11       Impact factor: 3.490

5.  Nitration of endogenous para-hydroxyphenylacetic acid and the metabolism of nitrotyrosine.

Authors:  Ali R Mani; Ananth S Pannala; Nelson N Orie; Richard Ollosson; David Harry; Catherine A Rice-Evans; Kevin P Moore
Journal:  Biochem J       Date:  2003-09-01       Impact factor: 3.857

6.  Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA.

Authors:  Alessia Liguori; Enrico Malito; Paola Lo Surdo; Luca Fagnocchi; Francesca Cantini; Andreas F Haag; Sébastien Brier; Mariagrazia Pizza; Isabel Delany; Matthew J Bottomley
Journal:  PLoS Pathog       Date:  2016-04-22       Impact factor: 6.823

7.  Host cell-derived lactate functions as an effector molecule in Neisseria meningitidis microcolony dispersal.

Authors:  Sara Sigurlásdóttir; Jakob Engman; Olaspers Sara Eriksson; Sunil D Saroj; Nadezda Zguna; Pilar Lloris-Garcerá; Leopold L Ilag; Ann-Beth Jonsson
Journal:  PLoS Pathog       Date:  2017-04-06       Impact factor: 6.823

8.  MtrR control of a transcriptional regulatory pathway in Neisseria meningitidis that influences expression of a gene (nadA) encoding a vaccine candidate.

Authors:  Jason M Cloward; William M Shafer
Journal:  PLoS One       Date:  2013-02-08       Impact factor: 3.240

9.  Microbial and metabolomic analysis of gingival crevicular fluid in general chronic periodontitis patients: lessons for a predictive, preventive, and personalized medical approach.

Authors:  Jun Pei; Fei Li; Youhua Xie; Jing Liu; Tian Yu; Xiping Feng
Journal:  EPMA J       Date:  2020-04-16       Impact factor: 6.543

10.  Optimization and Application of Electrochemical Transducer for Detection of Specific Oligonucleotide Sequence for Mycobacterium tuberculosis.

Authors:  Ricardo A M S Corrêa; Filipe S da Cruz; Cátia C Santos; Thiago C Pimenta; Diego L Franco; Lucas F Ferreira
Journal:  Biosensors (Basel)       Date:  2018-09-11
  10 in total

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