Literature DB >> 11995938

Anti-diabetic activity of alcoholic extract of Celosia argentea Linn. seeds in rats.

Thangarasu Vetrichelvan1, Maniappan Jegadeesan, Bangaru Adigalar Uma Devi.   

Abstract

Celosia argentea Linn. commonly known as "Cocks Comb" and its seeds are widely used in Indian folk medicine for the treatment of diabetes mellitus. This study was undertaken to evaluate the effect of an alcoholic extract of Celosia argentea seeds (ACAS) on blood glucose and body weight in alloxan-induced diabetic rats. ACAS was found to reduce the increase of blood glucose in alloxan-induced diabetic rats (27.8% at 250 mg/kg and 38.8% at 500 mg/kg body weight). Chronic administration of ACAS significantly (p<0.01) reduced the blood glucose in alloxan-induced diabetic rats for two weeks. Also the extract prevented a decrease in body weight in alloxan-induced diabetic rats. These results suggest that the ACAS possesses anti-diabetic activity in alloxan-induced diabetic rats.

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Year:  2002        PMID： 11995938     DOI： 10.1248/bpb.25.526

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  8 in total

1.  Anti-inflammatory and cytotoxic evaluation of extracts from the flowering stage of Celosia argentea.

Authors:  Oluwafunmilayo Dorcas Adegbaju; Gloria Aderonke Otunola; Anthony Jide Afolayan
Journal:  BMC Complement Med Ther       Date:  2020-05-24

Review 2.  Antidiabetic Potential of Syzygium sp.: An Overview.

Authors:  Azrin S Zulcafli; Chooiling Lim; Anna P Ling; Soimoi Chye; Rhunyian Koh
Journal:  Yale J Biol Med       Date:  2020-06-29

3.  Evaluation of hypoglycemic and anti-hyperglycemic potential of Tridax procumbens (Linn.).

Authors:  Hemant Pareek; Sameer Sharma; Balvant S Khajja; Kusum Jain; G C Jain
Journal:  BMC Complement Altern Med       Date:  2009-11-29       Impact factor: 3.659

4.  Investigation of in vivo antioxidant property of Abelmoschus esculentus (L) moench. fruit seed and peel powders in streptozotocin-induced diabetic rats.

Authors:  Vijayakumar Sabitha; Subramaniam Ramachandran; Koikaramparambil Robert Naveen; Kaliyamoorthy Panneerselvam
Journal:  J Ayurveda Integr Med       Date:  2012-10

5.  In-vitro α-amylase and α-glucosidase inhibitory activity of Adiantum caudatum Linn. and Celosia argentea Linn. extracts and fractions.

Authors:  Madhusudhan Telagari; Kirankumar Hullatti
Journal:  Indian J Pharmacol       Date:  2015 Jul-Aug       Impact factor: 1.200

6.  Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats.

Authors:  Bao-Zhong Diao; Wei-Rong Jin; Xue-Jing Yu
Journal:  Evid Based Complement Alternat Med       Date:  2014-06-30       Impact factor: 2.629

Review 7.  Betalains in Some Species of the Amaranthaceae Family: A Review.

Authors:  Maria Graça Miguel
Journal:  Antioxidants (Basel)       Date:  2018-04-04

8.  Methanolic extract of Celosia argentea var. crista leaves modulates glucose homeostasis and abates oxidative hepatic injury in diabetic rats.

Authors:  R U Hamzah; A R Lawal; F M Madaki; O L Erukainure
Journal:  Comp Clin Path       Date:  2018-04-09
  8 in total

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