Literature DB >> 11994399

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.

Jay D Horton1, Joseph L Goldstein, Michael S Brown.   

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Year:  2002        PMID: 11994399      PMCID: PMC150968          DOI: 10.1172/JCI15593

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  47 in total

Review 1.  Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis.

Authors:  Joseph L Goldstein; Robert B Rawson; Michael S Brown
Journal:  Arch Biochem Biophys       Date:  2002-01-15       Impact factor: 4.013

2.  Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

Authors:  H Shimano; I Shimomura; R E Hammer; J Herz; J L Goldstein; M S Brown; J D Horton
Journal:  J Clin Invest       Date:  1997-10-15       Impact factor: 14.808

3.  Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2.

Authors:  R Sato; J Inoue; Y Kawabe; T Kodama; T Takano; M Maeda
Journal:  J Biol Chem       Date:  1996-10-25       Impact factor: 5.157

Review 4.  The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor.

Authors:  M S Brown; J L Goldstein
Journal:  Cell       Date:  1997-05-02       Impact factor: 41.582

5.  Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B.

Authors:  Donald L Gillian-Daniel; Paul W Bates; Angie Tebon; Alan D Attie
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-19       Impact factor: 11.205

6.  Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein.

Authors:  X Hua; A Nohturfft; J L Goldstein; M S Brown
Journal:  Cell       Date:  1996-11-01       Impact factor: 41.582

7.  Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

Authors:  H Shimano; J D Horton; I Shimomura; R E Hammer; M S Brown; J L Goldstein
Journal:  J Clin Invest       Date:  1997-03-01       Impact factor: 14.808

8.  Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.

Authors:  I Shimomura; H Shimano; J D Horton; J L Goldstein; M S Brown
Journal:  J Clin Invest       Date:  1997-03-01       Impact factor: 14.808

9.  Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

Authors:  H Shimano; J D Horton; R E Hammer; I Shimomura; M S Brown; J L Goldstein
Journal:  J Clin Invest       Date:  1996-10-01       Impact factor: 14.808

10.  Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c.

Authors:  Guosheng Liang; Jian Yang; Jay D Horton; Robert E Hammer; Joseph L Goldstein; Michael S Brown
Journal:  J Biol Chem       Date:  2002-01-08       Impact factor: 5.157

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Authors:  Geoffrey F Gibbons
Journal:  Lipids       Date:  2002-12       Impact factor: 1.880

2.  Trajectory clustering: a non-parametric method for grouping gene expression time courses, with applications to mammary development.

Authors:  T L Phang; M C Neville; M Rudolph; L Hunter
Journal:  Pac Symp Biocomput       Date:  2003

Review 3.  Consequences of cellular cholesterol accumulation: basic concepts and physiological implications.

Authors:  Ira Tabas
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808

Review 4.  High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex.

Authors:  Colin Jefcoate
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808

5.  An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis.

Authors:  Dina S Stepanova; Galina Semenova; Yin-Ming Kuo; Andrew J Andrews; Sylwia Ammoun; C Oliver Hanemann; Jonathan Chernoff
Journal:  Cancer Res       Date:  2017-07-20       Impact factor: 12.701

6.  Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis.

Authors:  Rita T Brookheart; Chih-Yung S Lee; Peter J Espenshade
Journal:  J Biol Chem       Date:  2013-12-10       Impact factor: 5.157

Review 7.  Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis.

Authors:  W Gibson Wood; Ling Li; Walter E Müller; Gunter P Eckert
Journal:  J Neurochem       Date:  2014-01-02       Impact factor: 5.372

8.  Pharmacogenomics of sterol synthesis and statin use in schizophrenia subjects treated with antipsychotics.

Authors:  Thomas J Vassas; Kyle J Burghardt; Vicki L Ellingrod
Journal:  Pharmacogenomics       Date:  2014-01       Impact factor: 2.533

9.  Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs.

Authors:  Xuefen Xie; Hailing Liao; Huaixin Dang; Wei Pang; Youfei Guan; Xian Wang; John Y-J Shyy; Yi Zhu; Frances M Sladek
Journal:  Mol Endocrinol       Date:  2009-01-29

Review 10.  The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications.

Authors:  Oliver P Flint; Mustafa A Noor; Paul W Hruz; Phil B Hylemon; Kevin Yarasheski; Donald P Kotler; Rex A Parker; Aouatef Bellamine
Journal:  Toxicol Pathol       Date:  2009-01-26       Impact factor: 1.902

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