| Literature DB >> 11992779 |
Julia Castro1, Juan C Cuevas, José M Fiandor, Ma Teresa Fraile, Federico Gómez de las Heras, José R Ruiz.
Abstract
A number of new 2',3'-fused oxirane derivatives were synthesized for structure-activity relationship study. Many of these derivatives exhibit high potency against Candida spp. In addition, sordarin manno epoxide derivative 6 presents in vivo therapeutic effect in mice and is considered a promising antifungal lead within this series.Entities:
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Year: 2002 PMID： 11992779 DOI： 10.1016/s0960-894x(02)00168-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823