Literature DB >> 11992236

The role of von Willebrand factor in platelet function.

Philip G de Groot1.   

Abstract

von Willebrand factor (vWF) has essential functions in the very first stage of hemostasis. At the site of vascular damage vWF binds immediately to exposed collagens, thereby facilitating the adhesion of platelets. After a first layer of platelets has been formed, vWF is also crucial as a link between platelets in the forming thrombus. In this article, the current knowledge on the role of vWF in primary hemostasis is reviewed.

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Year:  2002        PMID： 11992236     DOI： 10.1055/s-2002-27815

Source DB:  PubMed          Journal:  Semin Thromb Hemost        ISSN： 0094-6176            Impact factor:   4.180


  4 in total

1.  Evaluation of the effect of 6 von Willebrand factor concentrates on platelet adhesion to human vein segments under flow conditions.

Authors:  Wolfgang Mouton; Jerzy Madon; Joerg Fehr; Thomas Bombeli
Journal:  Int J Hematol       Date:  2004-11       Impact factor: 2.490

Review 2.  Coagulopathy associated with traumatic brain injury.

Authors:  Monisha A Kumar
Journal:  Curr Neurol Neurosci Rep       Date:  2013-11       Impact factor: 5.081

Review 3.  Thyroid, hemostasis and thrombosis.

Authors:  F Marongiu; C Cauli; S Mariotti
Journal:  J Endocrinol Invest       Date:  2004-12       Impact factor: 4.256

4.  Establishment and characterization of a new and stable collagen-binding assay for the assessment of von Willebrand factor activity.

Authors:  Y Ni; J Nesrallah; M Agnew; F J Geske; E J Favaloro
Journal:  Int J Lab Hematol       Date:  2012-10-29       Impact factor: 2.877
  4 in total

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