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Literature DB >> 11991541

Exercise enhances and protects brain function.

Carl W Cotman¹, Christie Engesser-Cesar.

Abstract

Physical activity, in the form of voluntary wheel running, induces gene expression changes in the brain. Animals that exercise show an increase in brain-derived neurotrophic factor, a molecule that increases neuronal survival, enhances learning, and protects against cognitive decline. Microarray analysis of gene expression provides further support that exercise enhances and supports brain function.

Entities: Disease Gene

Mesh：

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Year: 2002 PMID： 11991541 DOI： 10.1097/00003677-200204000-00006

Source DB: PubMed Journal: Exerc Sport Sci Rev ISSN： 0091-6331 Impact factor: 6.230

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Cited

81 in total

Review 1. Motor enrichment and the induction of plasticity before or after brain injury.

Authors: Jeffrey A Kleim; Theresa A Jones; Timothy Schallert
Journal: Neurochem Res Date: 2003-11 Impact factor: 3.996

2. Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression.

Authors: Charles V Mobbs; Kelvin Yen; Jason Mastaitis; Ha Nguyen; Elizabeth Watson; Elisa Wurmbach; Stuart C Sealfon; Andrew Brooks; Stephen R J Salton
Journal: Neurochem Res Date: 2004-06 Impact factor: 3.996

3. Cognitive function in elderly marathon runners: cross-sectional data from the marathon trial (APSOEM).

Authors: Robert Winker; Ina Lukas; Thomas Perkmann; Helmut Haslacher; Elisabeth Ponocny; Johann Lehrner; Dimiter Tscholakoff; Peter Dal-Bianco
Journal: Wien Klin Wochenschr Date: 2010-11-15 Impact factor: 1.704

Review 4. Exercise offers anxiolytic potential: a role for stress and brain noradrenergic-galaninergic mechanisms.

Authors: Natale R Sciolino; Philip V Holmes
Journal: Neurosci Biobehav Rev Date: 2012-07-05 Impact factor: 8.989

5. Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis.

Authors: M A Beydoun; H A Beydoun; Y Wang
Journal: Obes Rev Date: 2008-03-06 Impact factor: 9.213

10. Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.

Authors: S Dato; M Soerensen; V Lagani; A Montesanto; G Passarino; K Christensen; Q Tan; L Christiansen
Journal: Exp Gerontol Date: 2014-01-22 Impact factor: 4.032

Exercise enhances and protects brain function.

Review 1. Motor enrichment and the induction of plasticity before or after brain injury.

2. Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression.

3. Cognitive function in elderly marathon runners: cross-sectional data from the marathon trial (APSOEM).

Review 4. Exercise offers anxiolytic potential: a role for stress and brain noradrenergic-galaninergic mechanisms.

5. Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis.

Review 6. Exercise, learned helplessness, and the stress-resistant brain.

7. Age, physical fitness, and attention: P3a and P3b.

8. Functional electrical stimulation in spinal cord injury:: from theory to practice.

Review 9. Cognitive reserve: implications for diagnosis and prevention of Alzheimer's disease.

10. Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.