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Literature DB >> 11990857

Emerging molecular markers of cancer.

Abstract

Alterations in gene sequences, expression levels and protein structure or function have been associated with every type of cancer. These 'molecular markers' can be useful in detecting cancer, determining prognosis and monitoring disease progression or therapeutic response. But what is the best way to identify molecular markers and can they be easily incorporated into the clinical setting?

Entities: Disease

Mesh：

Substances：
Genetic Markers
DNA

Year: 2002 PMID： 11990857 DOI： 10.1038/nrc755

Source DB: PubMed Journal: Nat Rev Cancer ISSN： 1474-175X Impact factor: 60.716

Keyword Cloud
Cited

161 in total

1. Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations.

Authors: Devin Dressman; Hai Yan; Giovanni Traverso; Kenneth W Kinzler; Bert Vogelstein
Journal: Proc Natl Acad Sci U S A Date: 2003-07-11 Impact factor: 11.205

2. Restriction endonuclease-catalyzed cleavage of DNA stimulates subsequent polymerase chain reaction and enables discrimination between normal and mutant K-RAS alleles.

Authors: I V Botezatu; O I Serdyuk; G I Potapova; V P Shelepov; A V Likhtenshtein
Journal: Dokl Biochem Biophys Date: 2003 Nov-Dec Impact factor: 0.788

3. Molecular diagnostics. At the nexus of individualized medicine, health care delivery, and public policy.

Authors: Scott A Waldman; Andre Terzic
Journal: Clin Transl Sci Date: 2009-02 Impact factor: 4.689

Review 4. Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer.

Authors: Joshua D Palmer; Nicholas G Zaorsky; Matthew Witek; Bo Lu
Journal: J Thorac Dis Date: 2014-04 Impact factor: 2.895

5. Differential exoprotease activities confer tumor-specific serum peptidome patterns.

Authors: Josep Villanueva; David R Shaffer; John Philip; Carlos A Chaparro; Hediye Erdjument-Bromage; Adam B Olshen; Martin Fleisher; Hans Lilja; Edi Brogi; Jeff Boyd; Marta Sanchez-Carbayo; Eric C Holland; Carlos Cordon-Cardo; Howard I Scher; Paul Tempst
Journal: J Clin Invest Date: 2006-01 Impact factor: 14.808

10. Single-wall carbon nanotube forest arrays for immunoelectrochemical measurement of four protein biomarkers for prostate cancer.

Authors: Bhaskara V Chikkaveeraiah; Ashwin Bhirde; Ruchika Malhotra; Vyomesh Patel; J Silvio Gutkind; James F Rusling
Journal: Anal Chem Date: 2009-11-01 Impact factor: 6.986

Emerging molecular markers of cancer.

1. Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations.

2. Restriction endonuclease-catalyzed cleavage of DNA stimulates subsequent polymerase chain reaction and enables discrimination between normal and mutant K-RAS alleles.

3. Molecular diagnostics. At the nexus of individualized medicine, health care delivery, and public policy.

Review 4. Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer.

5. Differential exoprotease activities confer tumor-specific serum peptidome patterns.

6. Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected]

7. Counterflow isotachophoresis as a method of concentration and isolation of DNA from biological fluids.

Review 8. Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies.

9. Potential use of quantitative tissue phenotype to predict malignant risk for oral premalignant lesions.

10. Single-wall carbon nanotube forest arrays for immunoelectrochemical measurement of four protein biomarkers for prostate cancer.