Literature DB >> 11990425

Microbial transformation of danazol.

M Iqbal Choudhary1.   

Abstract

Danazol (17beta-hydroxy-17alpha-pregna-2,4-dien-20-yno-[2,3-d] isoxazole) (1) on fermentation with Fusarium lini, Aspergillus niger, and Cephalosporium aphidicola yielded 17beta-hydroxy-2-(hydroxymethyl)-17-alpha-pregn-4-en-20-yn-3-one (2) and 17beta-hydroxy-2-(hydroxymethyl)-17 alpha-pregna-1,4-dien-20-yn-3-one (3), while the fermentation of 1 with Bacillus cerus yielded compound 2 only.

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Year:  2002        PMID： 11990425     DOI： 10.1080/10575630290019994

Source DB:  PubMed          Journal:  Nat Prod Lett        ISSN： 1026-8049


  2 in total

1.  Enhancing NMR Sensitivity of Natural-Abundance Low-γ Nuclei by Ultrafast Magic-Angle-Spinning Solid-State NMR Spectroscopy.

Authors:  Rongchun Zhang; Yitian Chen; Nair Rodriguez-Hornedo; Ayyalusamy Ramamoorthy
Journal:  Chemphyschem       Date:  2016-07-22       Impact factor: 3.102

2.  New Anti-Inflammatory Metabolites by Microbial Transformation of Medrysone.

Authors:  Saira Bano; Atia-Tul- Wahab; Sammer Yousuf; Almas Jabeen; Mohammad Ahmed Mesaik; Atta-Ur- Rahman; M Iqbal Choudhary
Journal:  PLoS One       Date:  2016-04-22       Impact factor: 3.240
  2 in total

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