Literature DB >> 11990106

Treatment of high-altitude pulmonary edema by bed rest and supplemental oxygen.

K Zafren1, J T Reeves, R Schoene.   

Abstract

STUDY
OBJECTIVES: We evaluated the safety and efficacy of treating high-altitude pulmonary edema (HAPE) by bed rest and supplemental oxygen at moderate altitudes. We also characterized clinical parameters in HAPE before and after treatment.
DESIGN: Case series.
SETTING: Two primary care centers at about 9,200 feet (2,800 meters) above sea level. TYPE OF PARTICIPANTS: All patients aged 16-69 years who had been diagnosed with HAPE and were treated with bed rest and supplemental oxygen. Patients were seen on a follow-up visit.
INTERVENTIONS: Selected patients were treated with bed rest and supplemental oxygen rather than hospital admission or descent. MAIN OUTCOME MEASURE: Patients were considered improved on follow-up if room air arterial oxygen saturation was increased by 10 percentage points or if their symptoms had improved.
RESULTS: Of 58 patients with confirmed HAPE, 25 (43%) were treated by bed rest and supplemental oxygen and were seen on return visits to the clinic. All of the treated patients improved at the return visit. Systolic blood pressure, heart rate, respiratory rate, and temperature decreased significantly between the first visit and the return visit. Oxygen saturation improved between visits.
CONCLUSION: Some patients with HAPE at moderate altitudes where medical facilities are available can be safely treated with bed rest and oxygen without descent.

Entities:  

Mesh:

Year:  1996        PMID: 11990106     DOI: 10.1580/1080-6032(1996)007[0127:tohape]2.3.co;2

Source DB:  PubMed          Journal:  Wilderness Environ Med        ISSN: 1080-6032            Impact factor:   1.518


  6 in total

1.  Management of high altitude pulmonary edema in the Himalaya: a review of 56 cases presenting at Pheriche medical aid post (4240 m).

Authors:  Barbara E Jones; Suzy Stokes; Suzi McKenzie; Eric Nilles; Gregory J Stoddard
Journal:  Wilderness Environ Med       Date:  2012-10-10       Impact factor: 1.518

Review 2.  Hypoxic pulmonary vasoconstriction.

Authors:  J T Sylvester; Larissa A Shimoda; Philip I Aaronson; Jeremy P T Ward
Journal:  Physiol Rev       Date:  2012-01       Impact factor: 46.500

3.  Standardization of methods for early diagnosis and on-site treatment of high-altitude pulmonary edema.

Authors:  Qiquan Zhou
Journal:  Pulm Med       Date:  2011-06-01

Review 4.  Interventions for treating acute high altitude illness.

Authors:  Daniel Simancas-Racines; Ingrid Arevalo-Rodriguez; Dimelza Osorio; Juan Va Franco; Yihan Xu; Ricardo Hidalgo
Journal:  Cochrane Database Syst Rev       Date:  2018-06-30

Review 5.  High-altitude illness: Management approach.

Authors:  Gökhan Aksel; Şeref Kerem Çorbacıoğlu; Can Özen
Journal:  Turk J Emerg Med       Date:  2019-09-19

Review 6.  Pulmonary Hypertension in Acute and Chronic High Altitude Maladaptation Disorders.

Authors:  Akylbek Sydykov; Argen Mamazhakypov; Abdirashit Maripov; Djuro Kosanovic; Norbert Weissmann; Hossein Ardeschir Ghofrani; Akpay Sh Sarybaev; Ralph Theo Schermuly
Journal:  Int J Environ Res Public Health       Date:  2021-02-10       Impact factor: 3.390

  6 in total

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