Literature DB >> 11990072

Isobolographic analysis of interaction between vigabatrin and baclofen in the formalin test in mice.

M Czuczwar1, J Kiś, A Potasiński, W A Turski, K Przesmycki.   

Abstract

Vigabatrin and baclofen given together, at doses not affecting motor performance, produced dose-dependent inhibition of both phases in the formalin test in mice. Isobolographic analysis revealed a significant synergy between both drugs in both phases of the forrmalin test.

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Year:  2001        PMID: 11990072

Source DB:  PubMed          Journal:  Pol J Pharmacol        ISSN: 1230-6002


  1 in total

1.  Neurobehavioral effects of vigabatrin and its ability to induce DNA damage in brain cells after acute treatment in rats.

Authors:  Karen Sousa; Natalia Decker; Thienne Rocha Pires; Débora Kuck Mausolff Papke; Vanessa Rodrigues Coelho; Pricila Pflüger; Patrícia Pereira; Jaqueline Nascimento Picada
Journal:  Psychopharmacology (Berl)       Date:  2016-09-27       Impact factor: 4.530

  1 in total

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