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Literature DB >> 11989543

Androgen therapy for anemia in elderly uremic patients.

Abstract

Androgens were the mainstay of treatment of renal anemia prior to the introduction of recombinant human erythropoietin. With the introduction of this recombinant hormone, the protocols of treatment of anemia were completely modified, and the use of androgens was relegated to the background. However, several authors have continued showing interest in the use of androgenic steroids for the treatment of anemia. This review examines several aspects of aging on androgenic hormones and hematopoiesis, the effects of androgen administration on hematological parameters, the side effects of these compounds and the future of this treatment for anemia in renal patients.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2001 PMID： 11989543 DOI： 10.1023/a:1014491110361

Source DB: PubMed Journal: Int Urol Nephrol ISSN： 0301-1623 Impact factor: 2.370

92 in total

1. Effects of hypophysectomy, castration, and testosterone propionate on hemopoiesis in the adult male rat.

Authors: R C CRAFTS
Journal: Endocrinology Date: 1946-12 Impact factor: 4.736

2. Contrasting effects of testosterone and stanozolol on serum lipoprotein levels.

Authors: P D Thompson; E M Cullinane; S P Sady; C Chenevert; A L Saritelli; M A Sady; P N Herbert
Journal: JAMA Date: 1989-02-24 Impact factor: 56.272

3. Nandrolone decanoate therapy for patients receiving hemodialysis. A controlled study.

Authors: J S Williams; J H Stein; T F Ferris
Journal: Arch Intern Med Date: 1974-08

4. Controlled study of androgen therapy in anemia of patients on maintenance hemodialysis.

Authors: E D Hendler; J A Goffinet; S Ross; R E Longnecker; V Bakovic
Journal: N Engl J Med Date: 1974-11-14 Impact factor: 91.245

5. Erythropoietin and erythropoiesis in anemic man following androgens.

Authors: R Alexanian
Journal: Blood Date: 1969-04 Impact factor: 22.113

6. Age-related declines in hematopoietic reserve capacity.

Authors: D A Lipschitz
Journal: Semin Oncol Date: 1995-02 Impact factor: 4.929

7. The effect of testosterone aromatization on high-density lipoprotein cholesterol level and postheparin lipolytic activity.

Authors: J M Zmuda; M C Fahrenbach; B T Younkin; L L Bausserman; R B Terry; D H Catlin; P D Thompson
Journal: Metabolism Date: 1993-04 Impact factor: 8.694

2. A systems-pharmacology analysis of herbal medicines used in health improvement treatment: predicting potential new drugs and targets.

Authors: Jianling Liu; Mengjie Pei; Chunli Zheng; Yan Li; Yonghua Wang; Aiping Lu; Ling Yang
Journal: Evid Based Complement Alternat Med Date: 2013-11-28 Impact factor: 2.629

2 in total

Androgen therapy for anemia in elderly uremic patients.

1. Effects of hypophysectomy, castration, and testosterone propionate on hemopoiesis in the adult male rat.

2. Contrasting effects of testosterone and stanozolol on serum lipoprotein levels.

3. Nandrolone decanoate therapy for patients receiving hemodialysis. A controlled study.

4. Controlled study of androgen therapy in anemia of patients on maintenance hemodialysis.

5. Erythropoietin and erythropoiesis in anemic man following androgens.

6. Age-related declines in hematopoietic reserve capacity.

7. The effect of testosterone aromatization on high-density lipoprotein cholesterol level and postheparin lipolytic activity.

8. Effect of age on hematopoiesis in man.

9. Iron status and anemia in the elderly: new findings and a review of previous studies.

Review 10. Atherogenic effects of anabolic steroids on serum lipid levels. A literature review.

1. Erythropoietin producing cells for potential cell therapy.

2. A systems-pharmacology analysis of herbal medicines used in health improvement treatment: predicting potential new drugs and targets.