Literature DB >> 11988863

Diphyllin acetylapioside, a 5-lipoxygenase inhibitor from Haplophyllum hispanicum.

José Ma Prieto, Rosa Ma Giner, Ma Carmen Recio Mf, Guillermo Schinella, Salvador Máñez, José Luis Ríos.   

Abstract

The topical anti-inflammatory activity of Haplophyllum hispanicum Spach is due to the presence of arylnaphthalene-type lignans acting as 5-lipoxygenase (5-LOX) inhibitors. The effects of the methanolic extract of this species on cellular systems have been determined by HPLC-DAD analysis. Diphyllin acetylapioside proved to be the main lignan endowed with 5-LOX inhibitory activity.

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Year:  2002        PMID： 11988863     DOI： 10.1055/s-2002-26747

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  3 in total

1.  A new species of Haplophyllum A. Juss. (Rutaceae) from the Iberian Peninsula: evidence from morphological, karyological and molecular analyses.

Authors:  F B Navarro; V N Suárez-Santiago; G Blanca
Journal:  Ann Bot       Date:  2004-08-11       Impact factor: 4.357

Review 2.  Molecular mechanism underlying anti-inflammatory and anti-allergic activities of phytochemicals: an update.

Authors:  Yuva Bellik; Laïd Boukraâ; Hasan A Alzahrani; Balkees A Bakhotmah; Fatiha Abdellah; Si M Hammoudi; Mokrane Iguer-Ouada
Journal:  Molecules       Date:  2012-12-27       Impact factor: 4.411

Review 3.  Animal Models of Inflammation for Screening of Anti-inflammatory Drugs: Implications for the Discovery and Development of Phytopharmaceuticals.

Authors:  Kalpesh R Patil; Umesh B Mahajan; Banappa S Unger; Sameer N Goyal; Sateesh Belemkar; Sanjay J Surana; Shreesh Ojha; Chandragouda R Patil
Journal:  Int J Mol Sci       Date:  2019-09-05       Impact factor: 5.923
  3 in total

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