Literature DB >> 11983155

Missing pieces in the NF-kappaB puzzle.

Sankar Ghosh1, Michael Karin.   

Abstract

The regulation of the transcription factor NF-kappaB activity occurs at several levels including controlled cytoplasmic-nuclear shuttling and modulation of its transcriptional activity. A critical component in NF-kappaB regulation is the IkappaB kinase (IKK) complex. This review is focused on recent progress as well as unanswered questions regarding the regulation and function of NF-kappaB and IKK.

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Year:  2002        PMID： 11983155     DOI： 10.1016/s0092-8674(02)00703-1

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  1136 in total

Review 1.  GSK-3: tricks of the trade for a multi-tasking kinase.

Authors:  Bradley W Doble; James R Woodgett
Journal:  J Cell Sci       Date:  2003-04-01       Impact factor: 5.285

2.  IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.

Authors:  Chris Albanese; Kongming Wu; Mark D'Amico; Christy Jarrett; David Joyce; Julian Hughes; James Hulit; Toshiyuki Sakamaki; Maofu Fu; Avri Ben-Ze'ev; Jacqueline F Bromberg; Carmela Lamberti; Udit Verma; Richard B Gaynor; Stephen W Byers; Richard G Pestell
Journal:  Mol Biol Cell       Date:  2003-02       Impact factor: 4.138

3.  The NFkappaB luciferase mouse: a new tool for real time measurement of NFkappaB activation in the whole animal.

Authors:  D A Mann
Journal:  Gut       Date:  2002-12       Impact factor: 23.059

4.  Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways.

Authors:  Rong Jiang; Ning-Ping Wang; Kenichi A Tanaka; Jerrold H Levy; Robert A Guyton; Zhi-Qing Zhao; Jakob Vinten-Johansen
Journal:  J Surg Res       Date:  2010-02-23       Impact factor: 2.192

5.  Testing NF-κB-based therapy in hemiparkinsonian monkeys.

Authors:  Susanta Mondal; Avik Roy; Arundhati Jana; Sankar Ghosh; Jeffrey H Kordower; Kalipada Pahan
Journal:  J Neuroimmune Pharmacol       Date:  2012-06-03       Impact factor: 4.147

6.  Neuronal Ablation of IKK2 Decreases Lesion Size and Improves Functional Outcome after Spinal Cord Injury in Mice.

Authors:  Ditte Gry Ellman; Hans Gram Novrup; Louise Helskov Jørgensen; Minna Christiansen Lund; Minna Yli-Karjanmaa; Pernille Marie Madsen; Jonas Heinrich Vienhues; Safinaz Dursun; John R Bethea; Karin Lykke-Hartmann; Roberta Brambilla; Kate Lykke Lambertsen
Journal:  JSM Neurosurg Spine       Date:  2017-08-10

Review 7.  MicroRNAs regulate the chaperone network in cerebral ischemia.

Authors:  Yi-Bing Ouyang; Rona G Giffard
Journal:  Transl Stroke Res       Date:  2013-08-17       Impact factor: 6.829

8.  Nanofiber-expanded human umbilical cord blood-derived CD34+ cell therapy accelerates murine cutaneous wound closure by attenuating pro-inflammatory factors and secreting IL-10.

Authors:  Suman Kanji; Manjusri Das; Reeva Aggarwal; Jingwei Lu; Matthew Joseph; Sujit Basu; Vincent J Pompili; Hiranmoy Das
Journal:  Stem Cell Res       Date:  2013-11-15       Impact factor: 2.020

9.  Targeted deletion of hepatocyte Ikkbeta confers growth advantages.

Authors:  Katherine S Koch; Shin Maeda; Guobin He; Michael Karin; Hyam L Leffert
Journal:  Biochem Biophys Res Commun       Date:  2009-01-24       Impact factor: 3.575

10.  Il-1 beta-induced post-transition effect of NF-kappaB provides time-dependent wave of signals for initial phase of intrapostatic inflammation.

Authors:  Eugene V Vykhovanets; Sanjeev Shukla; Gregory T MacLennan; Olena V Vykhovanets; Donald R Bodner; Sanjay Gupta
Journal:  Prostate       Date:  2009-05-01       Impact factor: 4.104
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