Literature DB >> 11981323

Genetics of rheumatoid arthritis: is there a scientific explanation for the human leukocyte antigen association?

Jane H Buckner1, Gerald T Nepom.   

Abstract

Human leukocyte antigen genes associated with rheumatoid arthritis are commonly found in the unaffected population, implying that causal mechanisms of disease involve interactions between these genes and other factors. A variety of approaches-genetic, structural, and immunologic-are used to explore possible molecular interactions that may contribute to understanding the basis for this disease association. The specific relation between human leukocyte antigen-DR4 alleles and rheumatoid arthritis remains one of the strongest and most thoroughly studied examples of human leukocyte antigen risk genes among human autoimmune disorders.

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Year:  2002        PMID： 11981323     DOI： 10.1097/00002281-200205000-00011

Source DB:  PubMed          Journal:  Curr Opin Rheumatol        ISSN： 1040-8711            Impact factor:   5.006


  11 in total

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Authors:  Jaymin Upadhyay; Christian Geber; Richard Hargreaves; Frank Birklein; David Borsook
Journal:  Neurosci Biobehav Rev       Date:  2017-08-12       Impact factor: 8.989

2.  Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles.

Authors:  S P Linn-Rasker; A H M van der Helm-van Mil; F A van Gaalen; M Kloppenburg; R R P de Vries; S le Cessie; F C Breedveld; R E M Toes; T W J Huizinga
Journal:  Ann Rheum Dis       Date:  2005-07-13       Impact factor: 19.103

3.  Differential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigens.

Authors:  Chao Jiang; Umesh S Deshmukh; Felicia Gaskin; Harini Bagavant; Julie Hanson; Chella S David; Shu Man Fu
Journal:  J Immunol       Date:  2009-12-09       Impact factor: 5.422

4.  Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis.

Authors:  Donald M Simons; Soyoung Oh; Elizabeth Kropf; Malinda Aitken; Victoria Garcia; Alissa Basehoar; Andrew J Caton
Journal:  J Immunol       Date:  2013-02-18       Impact factor: 5.422

5.  The Clinical Application of Anti-CCP in Rheumatoid Arthritis and Other Rheumatic Diseases.

Authors:  Ct Chou; Ht Liao; Ch Chen; Ws Chen; Hp Wang; Ky Su
Journal:  Biomark Insights       Date:  2007-05-03

Review 6.  The T cell cometh: interplay between adaptive immunity and cytokine networks in rheumatoid arthritis.

Authors:  Gary S Firestein
Journal:  J Clin Invest       Date:  2004-08       Impact factor: 14.808

7.  Association of rheumatoid factor production with FcgammaRIIIa polymorphism in Taiwanese rheumatoid arthritis.

Authors:  J-Y Chen; C-M Wang; J-M Wu; H-H Ho; S-F Luo
Journal:  Clin Exp Immunol       Date:  2006-04       Impact factor: 4.330

Review 8.  Antigen-specific tolerogenic and immunomodulatory strategies for the treatment of autoimmune arthritis.

Authors:  Shailesh R Satpute; Malarvizhi Durai; Kamal D Moudgil
Journal:  Semin Arthritis Rheum       Date:  2008-01-04       Impact factor: 5.532

9.  Persistent arthritis in Borrelia burgdorferi-infected HLA-DR4-positive CD28-negative mice post-antibiotic treatment.

Authors:  Bettina Panagiota Iliopoulou; Joseph Alroy; Brigitte T Huber
Journal:  Arthritis Rheum       Date:  2008-12

Review 10.  The role and clinical implications of G6PI in experimental models of rheumatoid arthritis.

Authors:  Thomas Kamradt; David Schubert
Journal:  Arthritis Res Ther       Date:  2004-11-30       Impact factor: 5.156
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