Literature DB >> 11980360

Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys.

Hiroshige Nakamura1, Ryuichi Morishita, Yasufumi Kaneda.   

Abstract

The number of reports on in vivo gene therapies with decoy ODNs complexed with HVJ liposomes has recently increased. Diligent efforts to improve HVJ vectors as gene carriers and to expand the therapeutic applications of NFkB and E2F decoy ODNs will be important for the improved treatment of many genetic diseases.

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Year:  2002        PMID： 11980360

Source DB:  PubMed          Journal:  In Vivo        ISSN： 0258-851X            Impact factor:   2.155


  3 in total

Review 1.  p38 MAPK inhibitors, IKK2 inhibitors, and TNFα inhibitors in COPD.

Authors:  Audreesh Banerjee; Cynthia Koziol-White; Reynold Panettieri
Journal:  Curr Opin Pharmacol       Date:  2012-02-24       Impact factor: 5.547

2.  Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis.

Authors:  Christopher G De Vry; Srinivasa Prasad; Laszlo Komuves; Carlos Lorenzana; Christi Parham; Tina Le; Sarvesh Adda; Jennifer Hoffman; Nicole Kahoud; Radhika Garlapati; Radha Shyamsundar; Kim Mai; Jie Zhang; Tony Muchamuel; Maya Dajee; Brian Schryver; Leslie M McEvoy; Rolf O Ehrhardt
Journal:  Gut       Date:  2006-09-01       Impact factor: 23.059

3.  Transcription factor decoy oligonucleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity.

Authors:  Rita Crinelli; Marzia Bianchi; Lucia Gentilini; Linda Palma; Mads D Sørensen; Torsten Bryld; Ravindra B Babu; Khalil Arar; Jesper Wengel; Mauro Magnani
Journal:  Nucleic Acids Res       Date:  2004-03-29       Impact factor: 16.971
  3 in total

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