Literature DB >> 11976444

Complex disease and the new clinical sciences.

Jonathan Rees1.   

Abstract

Medical research today is dominated by a genocentric point of view. At the same time, clinical discovery and patient-oriented research have become less common. Here, I suggest that these developments are interdependent, each representing the flip side of an inaccurate view of how clinical advance occurs.

Entities:  

Mesh:

Year:  2002        PMID: 11976444     DOI: 10.1126/science.296.5568.698

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  17 in total

1.  Campaign to revitalise academic medicine: is the bubble due to burst for medical research funding?

Authors:  Bruce G Charlton; Peter Andras
Journal:  BMJ       Date:  2004-07-31

Review 2.  Management of secondary-progressive multiple sclerosis.

Authors:  Gavin Giovannoni
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

3.  New take on comparative immunology: relevance to immunotherapy.

Authors:  Ena Wang; Adriana Albini; David F Stroncek; Francesco M Marincola
Journal:  Immunotherapy       Date:  2009-05       Impact factor: 4.196

4.  Why disease persists: an evolutionary nosology.

Authors:  Robert L Perlman
Journal:  Med Health Care Philos       Date:  2005

5.  Finding disease-related genomic experiments within an international repository: first steps in translational bioinformatics.

Authors:  Atul J Butte; Rong Chen
Journal:  AMIA Annu Symp Proc       Date:  2006

6.  The causation of disease - the practical and ethical consequences of competing explanations.

Authors:  Ulla Räisänen; Marie-Jet Bekkers; Paula Boddington; Srikant Sarangi; Angus Clarke
Journal:  Med Health Care Philos       Date:  2006

7.  Racial differences in family health history knowledge of type 2 diabetes: exploring the role of interpersonal mechanisms.

Authors:  Jielu Lin; Christopher S Marcum; Melanie F Myers; Laura M Koehly
Journal:  Transl Behav Med       Date:  2018-07-17       Impact factor: 3.046

Review 8.  Atrial fibrillation and cognitive function in patients with heart failure: a systematic review and meta-analysis.

Authors:  Pavlos G Myserlis; Antonia Malli; Dimitrios K Kalaitzoglou; Grigorios Kalaitzidis; Michael Miligkos; Damianos G Kokkinidis; Andreas P Kalogeropoulos
Journal:  Heart Fail Rev       Date:  2017-01       Impact factor: 4.214

9.  The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells.

Authors:  Javier A Menendez; Jorge Joven; Sílvia Cufí; Bruna Corominas-Faja; Cristina Oliveras-Ferraros; Elisabet Cuyàs; Begoña Martin-Castillo; Eugeni López-Bonet; Tomás Alarcón; Alejandro Vazquez-Martin
Journal:  Cell Cycle       Date:  2013-04-02       Impact factor: 4.534

Review 10.  After the genome--the phenome?

Authors:  C R Scriver
Journal:  J Inherit Metab Dis       Date:  2004       Impact factor: 4.982

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